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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
19.09
Human Site:
S579
Identified Species:
32.31
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S579
S
C
S
F
A
R
H
S
L
L
Q
T
L
Y
K
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S579
S
C
S
F
A
R
H
S
L
L
Q
T
L
Y
K
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
C633
P
A
R
C
P
Q
A
C
I
C
D
N
S
R
W
Dog
Lupus familis
XP_538355
1323
142434
S579
S
C
S
F
A
R
H
S
L
L
Q
T
L
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
N581
T
C
S
F
A
R
H
N
L
L
Q
T
L
Y
N
Rat
Rattus norvegicus
NP_001012199
431
46388
G424
N
S
G
R
S
C
C
G
W
V
Q
R
S
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
S581
S
C
P
L
A
R
H
S
L
L
Q
T
L
H
Q
Chicken
Gallus gallus
NP_001006237
580
63057
M572
S
C
S
F
A
R
H
M
L
L
Q
T
L
H
Q
Frog
Xenopus laevis
O13066
580
62889
T572
N
N
A
S
A
R
H
T
L
L
C
N
L
H
N
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
R558
V
C
S
S
A
R
D
R
L
K
N
T
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
T589
N
I
K
N
S
F
K
T
F
L
E
G
A
E
S
Honey Bee
Apis mellifera
XP_395378
580
63771
Q564
K
K
V
M
D
S
L
Q
D
S
K
D
S
L
K
Nematode Worm
Caenorhab. elegans
P34342
960
105635
A876
S
C
K
M
S
E
P
A
L
Q
R
A
I
E
V
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
S380
G
D
A
G
D
L
A
S
V
M
D
K
M
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
0
100
N.A.
80
6.6
N.A.
73.3
80
40
53.3
N.A.
6.6
6.6
20
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
26.6
N.A.
86.6
93.3
66.6
53.3
N.A.
33.3
13.3
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
58
0
15
8
0
0
0
8
8
0
0
% A
% Cys:
0
58
0
8
0
8
8
8
0
8
8
0
0
0
8
% C
% Asp:
0
8
0
0
15
0
8
0
8
0
15
8
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
0
0
15
0
% E
% Phe:
0
0
0
36
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
8
8
0
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
0
0
0
0
0
22
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
8
8
15
0
0
0
8
0
0
8
8
8
0
8
36
% K
% Leu:
0
0
0
8
0
8
8
0
65
58
0
0
58
8
8
% L
% Met:
0
0
0
15
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
22
8
0
8
0
0
0
8
0
0
8
15
0
0
15
% N
% Pro:
8
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
8
50
0
0
8
15
% Q
% Arg:
0
0
8
8
0
58
0
8
0
0
8
8
0
15
0
% R
% Ser:
43
8
43
15
22
8
0
36
0
8
0
0
22
0
8
% S
% Thr:
8
0
0
0
0
0
0
15
0
0
0
50
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
8
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _