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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL
All Species:
27.27
Human Site:
S166
Identified Species:
42.86
UniProt:
P46063
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46063
NP_002898.2
649
73457
S166
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Chimpanzee
Pan troglodytes
XP_520788
778
87498
S295
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Rhesus Macaque
Macaca mulatta
XP_001094207
778
87626
S295
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Dog
Lupus familis
XP_543768
646
73297
S166
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z129
648
72534
S166
T
M
L
N
A
S
S
S
K
E
H
V
K
W
V
Rat
Rattus norvegicus
Q6AYJ1
621
69624
T159
Q
Q
L
G
I
S
A
T
M
L
N
S
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
T472
T
Y
L
T
G
D
I
T
D
A
D
A
S
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038561
639
72081
S172
V
T
L
N
A
S
S
S
K
E
D
S
K
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
K812
K
S
L
S
G
E
Q
K
M
A
D
V
M
A
I
Honey Bee
Apis mellifera
XP_396807
583
66843
G122
L
P
A
V
I
S
K
G
I
T
I
V
V
S
P
Nematode Worm
Caenorhab. elegans
Q9TXJ8
631
71078
L161
V
V
S
P
L
I
S
L
V
E
D
Q
I
L
Q
Sea Urchin
Strong. purpuratus
XP_786769
920
101596
M279
S
R
K
D
T
E
T
M
A
E
N
L
K
K
G
Poplar Tree
Populus trichocarpa
XP_002304389
718
80947
S168
F
M
L
T
S
T
T
S
K
E
N
E
K
F
I
Maize
Zea mays
NP_001168975
710
80077
N164
Y
M
L
T
S
T
T
N
K
E
V
E
K
F
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FT73
705
79350
G164
Y
M
L
T
S
T
S
G
K
E
N
E
K
F
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
82.6
88.2
N.A.
84.9
79.6
N.A.
N.A.
26.3
N.A.
56.5
N.A.
20.1
46
43.1
35.6
Protein Similarity:
100
83.4
83.2
93.9
N.A.
92.5
88.2
N.A.
N.A.
37.7
N.A.
70.8
N.A.
30.6
63.7
61.3
49.3
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
N.A.
13.3
N.A.
60
N.A.
13.3
13.3
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
N.A.
20
N.A.
66.6
N.A.
26.6
13.3
20
46.6
Percent
Protein Identity:
39.2
39.4
N.A.
39
N.A.
N.A.
Protein Similarity:
58.6
57.4
N.A.
58.8
N.A.
N.A.
P-Site Identity:
40
33.3
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
80
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
40
0
7
0
7
14
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
0
7
0
27
0
0
0
0
% D
% Glu:
0
0
0
0
0
14
0
0
0
74
0
20
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
0
0
0
7
14
0
0
14
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
0
0
0
0
14
7
7
0
7
0
7
0
7
0
27
% I
% Lys:
7
0
7
0
0
0
7
7
60
0
0
0
67
14
0
% K
% Leu:
7
0
80
0
7
0
0
7
0
7
0
7
0
7
0
% L
% Met:
0
54
0
0
0
0
0
7
14
0
0
0
7
0
0
% M
% Asn:
0
0
0
40
0
0
0
7
0
0
27
0
0
0
0
% N
% Pro:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
7
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
7
7
7
20
54
54
47
0
0
0
14
14
14
7
% S
% Thr:
40
7
0
27
7
20
20
14
0
7
0
0
0
0
7
% T
% Val:
14
7
0
7
0
0
0
0
7
0
7
47
7
0
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% W
% Tyr:
14
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _