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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RECQL All Species: 20.61
Human Site: S603 Identified Species: 32.38
UniProt: P46063 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46063 NP_002898.2 649 73457 S603 N S F R A E S S Q T C H S E Q
Chimpanzee Pan troglodytes XP_520788 778 87498 S732 N S F R A E S S Q T C H S E Q
Rhesus Macaque Macaca mulatta XP_001094207 778 87626 S732 N S F R A E S S Q T C H S E Q
Dog Lupus familis XP_543768 646 73297 S603 S C F R I E S S Q T C H S E G
Cat Felis silvestris
Mouse Mus musculus Q9Z129 648 72534 S603 S S V R G A P S E A R Q V E Q
Rat Rattus norvegicus Q6AYJ1 621 69624 L578 K V G P R A S L L S N E G H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I920 1142 126164 Y1054 D D V V T S S Y F G G N A N Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038561 639 72081 R594 H S I T M K M R R R G T S Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 A1407 G N A N T S G A S G F N S F R
Honey Bee Apis mellifera XP_396807 583 66843 L539 G E A I I G H L L V N G Y L Q
Nematode Worm Caenorhab. elegans Q9TXJ8 631 71078 Y587 T V Y S V I S Y V V I G S K W
Sea Urchin Strong. purpuratus XP_786769 920 101596 S855 S F N R E N S S F T M S T S F
Poplar Tree Populus trichocarpa XP_002304389 718 80947 K675 S K I L D E I K K Y T G S E P
Maize Zea mays NP_001168975 710 80077 Q643 Q I S L L S S Q K P T T P A E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FT73 705 79350 S628 L S T Q Q I G S I S S Q K P V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 82.6 88.2 N.A. 84.9 79.6 N.A. N.A. 26.3 N.A. 56.5 N.A. 20.1 46 43.1 35.6
Protein Similarity: 100 83.4 83.2 93.9 N.A. 92.5 88.2 N.A. N.A. 37.7 N.A. 70.8 N.A. 30.6 63.7 61.3 49.3
P-Site Identity: 100 100 100 73.3 N.A. 33.3 6.6 N.A. N.A. 13.3 N.A. 13.3 N.A. 6.6 6.6 13.3 26.6
P-Site Similarity: 100 100 100 80 N.A. 46.6 13.3 N.A. N.A. 33.3 N.A. 40 N.A. 33.3 6.6 26.6 40
Percent
Protein Identity: 39.2 39.4 N.A. 39 N.A. N.A.
Protein Similarity: 58.6 57.4 N.A. 58.8 N.A. N.A.
P-Site Identity: 20 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: 33.3 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 20 14 0 7 0 7 0 0 7 7 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 27 0 0 0 0 % C
% Asp: 7 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 0 7 34 0 0 7 0 0 7 0 40 7 % E
% Phe: 0 7 27 0 0 0 0 0 14 0 7 0 0 7 7 % F
% Gly: 14 0 7 0 7 7 14 0 0 14 14 20 7 0 7 % G
% His: 7 0 0 0 0 0 7 0 0 0 0 27 0 7 0 % H
% Ile: 0 7 14 7 14 14 7 0 7 0 7 0 0 0 0 % I
% Lys: 7 7 0 0 0 7 0 7 14 0 0 0 7 7 0 % K
% Leu: 7 0 0 14 7 0 0 14 14 0 0 0 0 7 0 % L
% Met: 0 0 0 0 7 0 7 0 0 0 7 0 0 0 0 % M
% Asn: 20 7 7 7 0 7 0 0 0 0 14 14 0 7 0 % N
% Pro: 0 0 0 7 0 0 7 0 0 7 0 0 7 7 7 % P
% Gln: 7 0 0 7 7 0 0 7 27 0 0 14 0 7 40 % Q
% Arg: 0 0 0 40 7 0 0 7 7 7 7 0 0 0 7 % R
% Ser: 27 40 7 7 0 20 60 47 7 14 7 7 54 7 7 % S
% Thr: 7 0 7 7 14 0 0 0 0 34 14 14 7 0 0 % T
% Val: 0 14 14 7 7 0 0 0 7 14 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 7 0 0 0 0 14 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _