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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RECQL All Species: 31.21
Human Site: T511 Identified Species: 49.05
UniProt: P46063 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46063 NP_002898.2 649 73457 T511 E E L N E K L T P L K L I D S
Chimpanzee Pan troglodytes XP_520788 778 87498 T640 E E L N E K L T P L K L I D S
Rhesus Macaque Macaca mulatta XP_001094207 778 87626 T640 E E L N E K L T P L K L I D S
Dog Lupus familis XP_543768 646 73297 T511 E D L N E K L T P L K L I D S
Cat Felis silvestris
Mouse Mus musculus Q9Z129 648 72534 T511 E G L N E K L T P L K L I D T
Rat Rattus norvegicus Q6AYJ1 621 69624 A495 N I T E H C Q A L I K I L K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I920 1142 126164 T840 N T G S G R Y T L N M M V D I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038561 639 72081 D511 V E L A S S M D E K L T P L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 R1165 D L C S G R S R F T L L H I A
Honey Bee Apis mellifera XP_396807 583 66843 W456 A T H F E E S W T R S D C A E
Nematode Worm Caenorhab. elegans Q9TXJ8 631 71078 V503 C E N G N G F V G T S S K E S
Sea Urchin Strong. purpuratus XP_786769 920 101596 T695 Q K S A S G T T V L D R T D A
Poplar Tree Populus trichocarpa XP_002304389 718 80947 T512 Q E K D Q R L T M L Q L V D K
Maize Zea mays NP_001168975 710 80077 T508 Q L N D Q R A T L L Q L V D K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FT73 705 79350 T508 Q A K D Q R V T M L Q L G D K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 82.6 88.2 N.A. 84.9 79.6 N.A. N.A. 26.3 N.A. 56.5 N.A. 20.1 46 43.1 35.6
Protein Similarity: 100 83.4 83.2 93.9 N.A. 92.5 88.2 N.A. N.A. 37.7 N.A. 70.8 N.A. 30.6 63.7 61.3 49.3
P-Site Identity: 100 100 100 93.3 N.A. 86.6 6.6 N.A. N.A. 13.3 N.A. 13.3 N.A. 6.6 6.6 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. N.A. 40 N.A. 20 N.A. 33.3 13.3 20 40
Percent
Protein Identity: 39.2 39.4 N.A. 39 N.A. N.A.
Protein Similarity: 58.6 57.4 N.A. 58.8 N.A. N.A.
P-Site Identity: 40 26.6 N.A. 26.6 N.A. N.A.
P-Site Similarity: 80 66.6 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 14 0 0 7 7 0 0 0 0 0 7 14 % A
% Cys: 7 0 7 0 0 7 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 7 0 20 0 0 0 7 0 0 7 7 0 67 0 % D
% Glu: 34 40 0 7 40 7 0 0 7 0 0 0 0 7 7 % E
% Phe: 0 0 0 7 0 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 0 7 7 7 14 14 0 0 7 0 0 0 7 0 0 % G
% His: 0 0 7 0 7 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 7 0 7 34 7 7 % I
% Lys: 0 7 14 0 0 34 0 0 0 7 40 0 7 7 27 % K
% Leu: 0 14 40 0 0 0 40 0 20 60 14 60 7 7 0 % L
% Met: 0 0 0 0 0 0 7 0 14 0 7 7 0 0 0 % M
% Asn: 14 0 14 34 7 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 34 0 0 0 7 0 0 % P
% Gln: 27 0 0 0 20 0 7 0 0 0 20 0 0 0 7 % Q
% Arg: 0 0 0 0 0 34 0 7 0 7 0 7 0 0 0 % R
% Ser: 0 0 7 14 14 7 14 0 0 0 14 7 0 0 34 % S
% Thr: 0 14 7 0 0 0 7 67 7 14 0 7 7 0 7 % T
% Val: 7 0 0 0 0 0 7 7 7 0 0 0 20 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _