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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL
All Species:
42.12
Human Site:
Y188
Identified Species:
66.19
UniProt:
P46063
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46063
NP_002898.2
649
73457
Y188
N
S
E
L
K
L
I
Y
V
T
P
E
K
I
A
Chimpanzee
Pan troglodytes
XP_520788
778
87498
Y317
N
S
E
L
K
L
I
Y
V
T
P
E
K
I
A
Rhesus Macaque
Macaca mulatta
XP_001094207
778
87626
Y317
N
S
E
L
K
L
I
Y
V
T
P
E
K
I
A
Dog
Lupus familis
XP_543768
646
73297
Y188
N
S
K
L
K
L
I
Y
V
T
P
E
K
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z129
648
72534
Y188
N
S
Q
L
K
L
I
Y
V
T
P
E
K
I
A
Rat
Rattus norvegicus
Q6AYJ1
621
69624
N181
H
T
E
M
M
N
K
N
S
H
L
K
L
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
Y494
D
P
I
I
K
L
L
Y
V
T
P
E
K
V
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038561
639
72081
Y194
N
S
P
F
K
L
L
Y
V
T
P
E
K
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
Y834
P
P
M
V
K
L
L
Y
V
T
P
E
K
I
S
Honey Bee
Apis mellifera
XP_396807
583
66843
K143
D
Q
I
H
G
L
Q
K
H
N
V
K
A
G
M
Nematode Worm
Caenorhab. elegans
Q9TXJ8
631
71078
S184
S
S
L
N
A
N
T
S
K
E
E
A
K
R
V
Sea Urchin
Strong. purpuratus
XP_786769
920
101596
Q315
N
W
K
E
N
N
I
Q
V
V
V
A
T
V
A
Poplar Tree
Populus trichocarpa
XP_002304389
718
80947
Y190
E
G
E
L
K
I
L
Y
V
T
P
E
K
I
S
Maize
Zea mays
NP_001168975
710
80077
Y186
E
G
E
L
K
I
L
Y
V
T
P
E
K
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FT73
705
79350
Y186
E
D
D
L
K
I
L
Y
V
T
P
E
K
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
82.6
88.2
N.A.
84.9
79.6
N.A.
N.A.
26.3
N.A.
56.5
N.A.
20.1
46
43.1
35.6
Protein Similarity:
100
83.4
83.2
93.9
N.A.
92.5
88.2
N.A.
N.A.
37.7
N.A.
70.8
N.A.
30.6
63.7
61.3
49.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
53.3
N.A.
80
N.A.
60
6.6
13.3
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
N.A.
80
N.A.
86.6
N.A.
80
20
20
40
Percent
Protein Identity:
39.2
39.4
N.A.
39
N.A.
N.A.
Protein Similarity:
58.6
57.4
N.A.
58.8
N.A.
N.A.
P-Site Identity:
66.6
66.6
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
14
7
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
14
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
40
7
0
0
0
0
0
7
7
74
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
0
0
7
0
0
0
0
0
0
0
0
7
0
% G
% His:
7
0
0
7
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
14
7
0
20
40
0
0
0
0
0
0
67
0
% I
% Lys:
0
0
14
0
74
0
7
7
7
0
0
14
80
0
0
% K
% Leu:
0
0
7
54
0
60
40
0
0
0
7
0
7
0
0
% L
% Met:
0
0
7
7
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
47
0
0
7
7
20
0
7
0
7
0
0
0
0
0
% N
% Pro:
7
14
7
0
0
0
0
0
0
0
74
0
0
0
0
% P
% Gln:
0
7
7
0
0
0
7
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
47
0
0
0
0
0
7
7
0
0
0
0
0
27
% S
% Thr:
0
7
0
0
0
0
7
0
0
74
0
0
7
0
0
% T
% Val:
0
0
0
7
0
0
0
0
80
7
14
0
0
20
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _