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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RECQL All Species: 42.73
Human Site: Y235 Identified Species: 67.14
UniProt: P46063 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46063 NP_002898.2 649 73457 Y235 G H D F R P D Y K A L G I L K
Chimpanzee Pan troglodytes XP_520788 778 87498 Y364 G H D F R P D Y K A L G I L K
Rhesus Macaque Macaca mulatta XP_001094207 778 87626 Y364 G H D F R P D Y K A L G I L K
Dog Lupus familis XP_543768 646 73297 Y235 G H D F R P D Y K A L G I L K
Cat Felis silvestris
Mouse Mus musculus Q9Z129 648 72534 Y235 G H D F R P D Y K A L G I L K
Rat Rattus norvegicus Q6AYJ1 621 69624 G228 V H C C S Q W G H D F R P D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I920 1142 126164 Y541 G H D F R K D Y K R L N M L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038561 639 72081 Y241 G H D F R P D Y K L L G I L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 Y881 G H D F R P D Y K K L G V L K
Honey Bee Apis mellifera XP_396807 583 66843 F190 Y M A K S N R F M N K L Q K A
Nematode Worm Caenorhab. elegans Q9TXJ8 631 71078 L231 K S L S V G F L K L I A I D E
Sea Urchin Strong. purpuratus XP_786769 920 101596 R362 G R D D E P A R C I V Y Y G I
Poplar Tree Populus trichocarpa XP_002304389 718 80947 Y237 G H D F R P D Y K S L S I L K
Maize Zea mays NP_001168975 710 80077 Y233 G H D F R P D Y K N L G I L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FT73 705 79350 Y233 G H D F R P D Y K N L S I L K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.1 82.6 88.2 N.A. 84.9 79.6 N.A. N.A. 26.3 N.A. 56.5 N.A. 20.1 46 43.1 35.6
Protein Similarity: 100 83.4 83.2 93.9 N.A. 92.5 88.2 N.A. N.A. 37.7 N.A. 70.8 N.A. 30.6 63.7 61.3 49.3
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 66.6 N.A. 93.3 N.A. 86.6 0 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 80 N.A. 93.3 N.A. 93.3 6.6 26.6 26.6
Percent
Protein Identity: 39.2 39.4 N.A. 39 N.A. N.A.
Protein Similarity: 58.6 57.4 N.A. 58.8 N.A. N.A.
P-Site Identity: 86.6 93.3 N.A. 86.6 N.A. N.A.
P-Site Similarity: 93.3 93.3 N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 0 34 0 7 0 0 7 % A
% Cys: 0 0 7 7 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 80 7 0 0 74 0 0 7 0 0 0 14 0 % D
% Glu: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % E
% Phe: 0 0 0 74 0 0 7 7 0 0 7 0 0 0 0 % F
% Gly: 80 0 0 0 0 7 0 7 0 0 0 54 0 7 0 % G
% His: 0 80 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 7 0 67 0 7 % I
% Lys: 7 0 0 7 0 7 0 0 80 7 7 0 0 7 67 % K
% Leu: 0 0 7 0 0 0 0 7 0 14 74 7 0 74 0 % L
% Met: 0 7 0 0 0 0 0 0 7 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 7 0 0 0 20 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 74 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 7 0 0 74 0 7 7 0 7 0 7 0 0 7 % R
% Ser: 0 7 0 7 14 0 0 0 0 7 0 14 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 0 0 0 7 0 0 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 74 0 0 0 7 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _