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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL
All Species:
37.27
Human Site:
Y288
Identified Species:
58.57
UniProt:
P46063
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46063
NP_002898.2
649
73457
Y288
F
N
R
P
N
L
Y
Y
E
V
R
Q
K
P
S
Chimpanzee
Pan troglodytes
XP_520788
778
87498
Y417
F
N
R
P
N
L
Y
Y
E
V
R
Q
K
P
S
Rhesus Macaque
Macaca mulatta
XP_001094207
778
87626
Y417
F
N
R
S
N
L
Y
Y
E
V
R
Q
K
P
S
Dog
Lupus familis
XP_543768
646
73297
Y288
F
N
R
P
N
L
Y
Y
E
I
R
Q
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z129
648
72534
Y288
F
N
R
P
N
L
F
Y
E
V
R
Q
K
P
S
Rat
Rattus norvegicus
Q6AYJ1
621
69624
F281
C
L
T
F
T
A
S
F
N
R
P
N
L
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
Y594
F
N
R
H
N
L
K
Y
D
V
L
P
K
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038561
639
72081
Y294
F
N
R
P
N
L
Y
Y
E
V
R
F
K
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
Y934
F
N
R
S
N
L
R
Y
R
V
L
P
K
K
G
Honey Bee
Apis mellifera
XP_396807
583
66843
L243
P
G
V
P
I
L
G
L
T
A
T
A
P
A
K
Nematode Worm
Caenorhab. elegans
Q9TXJ8
631
71078
K284
S
N
V
L
D
D
V
K
D
M
L
G
I
Q
A
Sea Urchin
Strong. purpuratus
XP_786769
920
101596
W415
G
Q
H
F
G
E
R
W
E
G
Q
A
R
C
N
Poplar Tree
Populus trichocarpa
XP_002304389
718
80947
Y290
V
N
R
P
N
L
F
Y
T
V
R
S
K
S
S
Maize
Zea mays
NP_001168975
710
80077
Y286
V
N
R
P
N
L
F
Y
K
V
S
E
K
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FT73
705
79350
Y286
V
N
R
P
N
L
F
Y
S
V
R
E
K
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.1
82.6
88.2
N.A.
84.9
79.6
N.A.
N.A.
26.3
N.A.
56.5
N.A.
20.1
46
43.1
35.6
Protein Similarity:
100
83.4
83.2
93.9
N.A.
92.5
88.2
N.A.
N.A.
37.7
N.A.
70.8
N.A.
30.6
63.7
61.3
49.3
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
0
N.A.
N.A.
53.3
N.A.
80
N.A.
53.3
13.3
6.6
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
6.6
N.A.
N.A.
60
N.A.
86.6
N.A.
53.3
13.3
33.3
33.3
Percent
Protein Identity:
39.2
39.4
N.A.
39
N.A.
N.A.
Protein Similarity:
58.6
57.4
N.A.
58.8
N.A.
N.A.
P-Site Identity:
66.6
53.3
N.A.
60
N.A.
N.A.
P-Site Similarity:
73.3
73.3
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
7
0
14
0
7
14
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
7
7
0
0
14
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
7
0
0
47
0
0
14
0
0
0
% E
% Phe:
54
0
0
14
0
0
27
7
0
0
0
7
0
0
0
% F
% Gly:
7
7
0
0
7
0
7
0
0
7
0
7
0
0
7
% G
% His:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
0
7
7
7
0
0
0
74
14
7
% K
% Leu:
0
7
0
7
0
80
0
7
0
0
20
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
80
0
0
74
0
0
0
7
0
0
7
0
0
14
% N
% Pro:
7
0
0
60
0
0
0
0
0
0
7
14
7
34
14
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
7
34
0
7
0
% Q
% Arg:
0
0
74
0
0
0
14
0
7
7
54
0
7
0
0
% R
% Ser:
7
0
0
14
0
0
7
0
7
0
7
7
0
20
40
% S
% Thr:
0
0
7
0
7
0
0
0
14
0
7
0
0
0
0
% T
% Val:
20
0
14
0
0
0
7
0
0
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
34
74
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _