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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 19.09
Human Site: S594 Identified Species: 32.31
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 S594 F S N S I P Q S Q T G N S E T
Chimpanzee Pan troglodytes XP_001162276 812 89269 S594 F S N S I P Q S Q T G N S E T
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 S593 F S N S I P Q S E T G N S E T
Dog Lupus familis XP_854432 985 108067 S765 F S N S I P Q S Q T G N S A A
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 P579 F S N S I P Q P H A G N S A A
Rat Rattus norvegicus XP_235295 772 84951 P574 F S N S I P Q P H S G N S A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 R487 K D E K D I L R C A H L Q K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 E523 S I M V E E N E W V V D Y A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 T645 F S N T I P I T K E Q Q E E D
Honey Bee Apis mellifera XP_001121968 582 67009 K387 S H I A A L M K N T G V L F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 S871 L S N K I P D S E K K E S E P
Poplar Tree Populus trichocarpa XP_002300386 476 53332 Q281 K T S E D I E Q C A H L Q K Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 T476 G G Y I V Y S T C S V M I P E
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 P423 D R I L L D A P C S G T G V I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 93.3 86.6 N.A. 66.6 66.6 N.A. N.A. 0 N.A. 0 N.A. 40 13.3 N.A. 46.6
P-Site Similarity: 100 100 100 86.6 N.A. 66.6 73.3 N.A. N.A. 6.6 N.A. 6.6 N.A. 60 26.6 N.A. 53.3
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 0 0 22 0 0 0 29 22 % A
% Cys: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 15 8 8 0 0 0 0 8 0 0 8 % D
% Glu: 0 0 8 8 8 8 8 8 15 8 0 8 8 36 15 % E
% Phe: 50 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 8 0 0 0 0 0 0 0 0 58 0 8 0 0 % G
% His: 0 8 0 0 0 0 0 0 15 0 15 0 0 0 0 % H
% Ile: 0 8 15 8 58 15 8 0 0 0 0 0 8 0 8 % I
% Lys: 15 0 0 15 0 0 0 8 8 8 8 0 0 15 0 % K
% Leu: 8 0 0 8 8 8 8 0 0 0 0 15 8 0 8 % L
% Met: 0 0 8 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 58 0 0 0 8 0 8 0 0 43 0 0 0 % N
% Pro: 0 0 0 0 0 58 0 22 0 0 0 0 0 8 8 % P
% Gln: 0 0 0 0 0 0 43 8 22 0 8 8 15 0 8 % Q
% Arg: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 15 58 8 43 0 0 8 36 0 22 0 0 50 0 8 % S
% Thr: 0 8 0 8 0 0 0 15 0 36 0 8 0 0 22 % T
% Val: 0 0 0 8 8 0 0 0 0 8 15 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _