Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 20.61
Human Site: S599 Identified Species: 34.87
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 S599 P Q S Q T G N S E T A T P T N
Chimpanzee Pan troglodytes XP_001162276 812 89269 S599 P Q S Q T G N S E T A T P T N
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 S598 P Q S E T G N S E T A T P K N
Dog Lupus familis XP_854432 985 108067 S770 P Q S Q T G N S A A S T P T S
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 S584 P Q P H A G N S A A A T P T E
Rat Rattus norvegicus XP_235295 772 84951 S579 P Q P H S G N S A A G T P T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 Q492 I L R C A H L Q K E L L L S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 Y528 E N E W V V D Y A L K K R N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 E650 P I T K E Q Q E E D E K Q L D
Honey Bee Apis mellifera XP_001121968 582 67009 L392 L M K N T G V L F S N D V N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 S876 P D S E K K E S E P A N D G D
Poplar Tree Populus trichocarpa XP_002300386 476 53332 Q286 I E Q C A H L Q K Q L L L A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 I481 Y S T C S V M I P E N E A V I
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 G428 D A P C S G T G V I G K D Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 86.6 73.3 N.A. 60 53.3 N.A. N.A. 0 N.A. 0 N.A. 13.3 13.3 N.A. 33.3
P-Site Similarity: 100 100 93.3 86.6 N.A. 60 60 N.A. N.A. 13.3 N.A. 6.6 N.A. 33.3 20 N.A. 46.6
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 22 0 0 0 29 22 36 0 8 8 15 % A
% Cys: 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 8 0 0 8 0 8 15 0 15 % D
% Glu: 8 8 8 15 8 0 8 8 36 15 8 8 0 0 22 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 58 0 8 0 0 15 0 0 8 0 % G
% His: 0 0 0 15 0 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 8 0 0 0 0 0 8 0 8 0 0 0 0 8 % I
% Lys: 0 0 8 8 8 8 0 0 15 0 8 22 0 8 0 % K
% Leu: 8 8 0 0 0 0 15 8 0 8 15 15 15 8 0 % L
% Met: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 43 0 0 0 15 8 0 15 22 % N
% Pro: 58 0 22 0 0 0 0 0 8 8 0 0 43 0 0 % P
% Gln: 0 43 8 22 0 8 8 15 0 8 0 0 8 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 0 8 36 0 22 0 0 50 0 8 8 0 0 8 15 % S
% Thr: 0 0 15 0 36 0 8 0 0 22 0 43 0 36 0 % T
% Val: 0 0 0 0 8 15 8 0 8 0 0 0 8 8 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _