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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
10.91
Human Site:
S616
Identified Species:
18.46
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
S616
L
P
Q
V
I
P
K
S
E
N
S
S
Q
P
A
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
S616
L
P
Q
V
I
P
K
S
E
N
S
S
Q
P
A
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
S615
L
P
Q
V
I
P
K
S
E
N
S
S
Q
P
A
Dog
Lupus familis
XP_854432
985
108067
V787
L
P
E
V
K
G
Q
V
T
P
K
P
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
K601
L
K
D
Q
V
T
P
K
S
E
N
G
S
Q
P
Rat
Rattus norvegicus
XP_235295
772
84951
K596
L
K
G
Q
V
T
P
K
S
E
N
S
S
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
T509
S
V
N
A
T
S
E
T
G
G
Y
I
V
Y
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
G545
V
P
T
G
L
D
F
G
K
E
G
F
T
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
E667
I
E
A
D
A
T
T
E
A
A
A
E
S
E
E
Honey Bee
Apis mellifera
XP_001121968
582
67009
F409
I
K
A
V
V
G
N
F
H
R
L
G
I
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
E893
E
P
V
E
M
K
G
E
E
E
Q
V
T
M
E
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
S303
M
V
D
A
N
S
K
S
G
G
Y
I
V
Y
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
K498
A
L
K
N
R
D
V
K
L
V
P
C
G
L
D
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
F445
V
S
R
T
E
K
D
F
I
Q
I
P
H
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
100
100
20
N.A.
6.6
13.3
N.A.
N.A.
0
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
46.6
N.A.
20
26.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
15
8
0
0
0
8
8
8
0
0
0
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
0
15
8
0
15
8
0
0
0
0
0
0
0
8
% D
% Glu:
8
8
8
8
8
0
8
15
29
29
0
8
8
8
15
% E
% Phe:
0
0
0
0
0
0
8
15
0
0
0
8
0
0
8
% F
% Gly:
0
0
8
8
0
15
8
8
15
15
8
15
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
15
0
0
0
22
0
0
0
8
0
8
15
8
0
0
% I
% Lys:
0
22
8
0
8
15
29
22
8
0
8
0
0
0
0
% K
% Leu:
43
8
0
0
8
0
0
0
8
0
8
0
0
15
0
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
8
0
8
0
0
22
15
0
0
0
8
% N
% Pro:
0
43
0
0
0
22
15
0
0
8
8
15
0
22
15
% P
% Gln:
0
0
22
15
0
0
8
0
0
8
8
0
22
15
8
% Q
% Arg:
0
0
8
0
8
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
8
8
0
0
0
15
0
29
15
0
22
29
22
0
15
% S
% Thr:
0
0
8
8
8
22
8
8
8
0
0
0
15
8
0
% T
% Val:
15
15
8
36
22
0
8
8
0
8
0
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
15
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _