KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
8.79
Human Site:
S646
Identified Species:
14.87
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
S646
Q
Q
H
P
K
K
A
S
F
Q
K
L
N
G
I
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
S646
Q
Q
H
P
K
K
A
S
F
Q
K
L
N
G
I
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
S645
Q
Q
R
P
K
K
A
S
F
Q
K
P
N
G
T
Dog
Lupus familis
XP_854432
985
108067
P817
Q
L
Q
K
R
Q
H
P
K
K
A
S
F
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
P631
R
Q
P
H
S
K
K
P
F
Q
K
L
N
G
I
Rat
Rattus norvegicus
XP_235295
772
84951
P626
G
Q
Q
H
S
K
K
P
F
Q
K
M
N
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
R539
A
L
K
K
R
N
V
R
L
V
A
T
G
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
D575
Y
P
H
S
H
N
M
D
G
F
F
V
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
P697
L
G
K
R
A
G
K
P
S
F
T
E
I
E
Q
Honey Bee
Apis mellifera
XP_001121968
582
67009
L439
K
N
F
D
R
V
L
L
D
A
P
C
T
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
G923
G
S
P
K
K
Q
N
G
K
M
K
D
G
Q
K
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
K333
A
L
K
K
R
N
V
K
L
V
P
C
G
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
R528
P
S
L
E
K
T
R
R
F
Y
P
H
V
H
N
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
Y475
K
H
G
G
V
I
V
Y
S
T
C
S
V
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
100
80
6.6
N.A.
60
53.3
N.A.
N.A.
0
N.A.
6.6
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
80
26.6
N.A.
66.6
60
N.A.
N.A.
6.6
N.A.
20
N.A.
0
20
N.A.
20
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
8
0
22
0
0
8
15
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
15
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
8
0
0
8
0
0
15
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
43
15
8
0
8
0
0
% F
% Gly:
15
8
8
8
0
8
0
8
8
0
0
0
22
43
0
% G
% His:
0
8
22
15
8
0
8
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
29
% I
% Lys:
15
0
22
29
36
36
22
8
15
8
43
0
0
8
15
% K
% Leu:
8
22
8
0
0
0
8
8
15
0
0
22
0
15
8
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
22
8
0
0
0
0
0
36
0
8
% N
% Pro:
8
8
15
22
0
0
0
29
0
0
22
8
0
0
0
% P
% Gln:
29
36
15
0
0
15
0
0
0
36
0
0
0
15
8
% Q
% Arg:
8
0
8
8
29
0
8
15
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
8
15
0
0
22
15
0
0
15
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
8
8
8
0
15
% T
% Val:
0
0
0
0
8
8
22
0
0
15
0
8
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _