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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
10.61
Human Site:
S659
Identified Species:
17.95
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
S659
G
I
S
K
G
A
D
S
E
L
S
T
V
P
S
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
S659
G
I
S
K
G
A
D
S
E
L
S
T
V
P
S
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
S658
G
T
S
K
G
A
D
S
E
L
S
T
V
P
S
Dog
Lupus familis
XP_854432
985
108067
K830
Q
K
Q
N
G
I
S
K
G
T
D
S
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
L644
G
I
A
K
G
P
G
L
S
T
E
P
S
V
P
Rat
Rattus norvegicus
XP_235295
772
84951
L639
G
I
S
K
G
P
G
L
P
T
E
P
S
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
F552
L
D
F
G
K
E
G
F
T
R
F
K
D
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
T588
K
L
K
K
L
S
N
T
I
P
T
A
P
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
K710
E
Q
E
L
K
K
K
K
R
E
E
S
K
T
K
Honey Bee
Apis mellifera
XP_001121968
582
67009
D452
G
T
G
V
V
S
K
D
P
S
V
K
T
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
G936
Q
K
G
K
V
D
E
G
K
G
Q
G
G
N
G
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
F346
L
D
F
G
R
P
G
F
V
R
F
R
Q
H
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
V541
H
N
M
D
G
F
F
V
A
K
L
K
K
M
S
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
V488
A
V
E
E
D
E
A
V
I
D
Y
A
L
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
100
93.3
13.3
N.A.
26.6
33.3
N.A.
N.A.
0
N.A.
6.6
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
33.3
33.3
N.A.
N.A.
0
N.A.
40
N.A.
6.6
13.3
N.A.
20
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
22
8
0
8
0
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
8
8
8
22
8
0
8
8
0
8
0
0
% D
% Glu:
8
0
15
8
0
15
8
0
22
8
22
0
0
0
8
% E
% Phe:
0
0
15
0
0
8
8
15
0
0
15
0
0
0
0
% F
% Gly:
43
0
15
15
50
0
29
8
8
8
0
8
15
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
29
0
0
0
8
0
0
15
0
0
0
0
0
0
% I
% Lys:
8
15
8
50
15
8
15
15
8
8
0
22
15
8
22
% K
% Leu:
15
8
0
8
8
0
0
15
0
22
8
0
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
0
8
0
0
8
0
0
0
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
22
0
0
15
8
0
15
8
22
15
% P
% Gln:
15
8
8
0
0
0
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
15
0
8
0
15
15
% R
% Ser:
0
0
29
0
0
15
8
22
8
8
22
15
15
0
36
% S
% Thr:
0
15
0
0
0
0
0
8
8
22
8
22
8
8
0
% T
% Val:
0
8
0
8
15
0
0
15
8
0
8
0
22
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _