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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 8.48
Human Site: S679 Identified Species: 14.36
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 S679 A S S S F Q D S S Q P A G K A
Chimpanzee Pan troglodytes XP_001162276 812 89269 S679 A S S S F Q D S S Q P A G K A
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 S678 A S S R C Q D S S Q P A G K A
Dog Lupus familis XP_854432 985 108067 K850 T K S Q A S S K L Q D S S Q P
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 G664 T R P S Q S A G N A D V N S K
Rat Rattus norvegicus XP_235295 772 84951 L659 A R P Q E S S L S D V K R K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 P572 K S T R R F Y P H T H N M D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 A608 E S L V M E T A A S S E M K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 P730 F E Q P V K K P K P E K P A E
Honey Bee Apis mellifera XP_001121968 582 67009 R472 Q R C C T L Q R E L L L A A I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 K956 T M S P A V Q K R N K K R K D
Poplar Tree Populus trichocarpa XP_002300386 476 53332 P366 E K T R R F Y P H V H N M D G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 V561 S G N D E P A V T M E Q A Q V
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 I508 L V D T G L A I G K E A F T S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 86.6 13.3 N.A. 6.6 20 N.A. N.A. 6.6 N.A. 13.3 N.A. 0 0 N.A. 13.3
P-Site Similarity: 100 100 86.6 26.6 N.A. 13.3 20 N.A. N.A. 13.3 N.A. 33.3 N.A. 6.6 0 N.A. 13.3
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 0 6.6 N.A.
P-Site Similarity: 6.6 N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 0 15 0 22 8 8 8 0 29 15 15 22 % A
% Cys: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 22 0 0 8 15 0 0 15 8 % D
% Glu: 15 8 0 0 15 8 0 0 8 0 22 8 0 0 15 % E
% Phe: 8 0 0 0 15 15 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 0 0 8 0 0 8 8 0 0 0 22 0 15 % G
% His: 0 0 0 0 0 0 0 0 15 0 15 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % I
% Lys: 8 15 0 0 0 8 8 15 8 8 8 22 0 43 8 % K
% Leu: 8 0 8 0 0 15 0 8 8 8 8 8 0 0 0 % L
% Met: 0 8 0 0 8 0 0 0 0 8 0 0 22 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 8 8 0 15 8 0 0 % N
% Pro: 0 0 15 15 0 8 0 22 0 8 22 0 8 0 8 % P
% Gln: 8 0 8 15 8 22 15 0 0 29 0 8 0 15 0 % Q
% Arg: 0 22 0 22 15 0 0 8 8 0 0 0 15 0 8 % R
% Ser: 8 36 36 22 0 22 15 22 29 8 8 8 8 8 8 % S
% Thr: 22 0 15 8 8 0 8 0 8 8 0 0 0 8 0 % T
% Val: 0 8 0 8 8 8 0 8 0 8 8 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _