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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 21.82
Human Site: S791 Identified Species: 36.92
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 S791 T V S P I R S S R P P P A K R
Chimpanzee Pan troglodytes XP_001162276 812 89269 S791 T V S P I R S S R L P P A K R
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 S790 T V S P I S S S R P P P A K R
Dog Lupus familis XP_854432 985 108067 S964 A M S P L D S S Q P P P A K R
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 T772 F V S P H S S T R P P P A K R
Rat Rattus norvegicus XP_235295 772 84951 T751 T T A H H S S T R P P P A K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 P662 L K A V R P S P H K S H A P V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 L713 K T K K K N L L K K K K N R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 T821 S K S A I K E T K T K P Q P K
Honey Bee Apis mellifera XP_001121968 582 67009 A562 N M D G F F V A K L K K F S N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 G1055 P K S F G G K G A S S A A F R
Poplar Tree Populus trichocarpa XP_002300386 476 53332 R456 E I S K S R R R K E Q L I E R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 A651 W K N E I A Q A R E E K R K T
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 V598 D K Y I E K S V K N N L L K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 93.3 93.3 66.6 N.A. 73.3 60 N.A. N.A. 13.3 N.A. 0 N.A. 20 0 N.A. 20
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 80 73.3 N.A. N.A. 20 N.A. 13.3 N.A. 53.3 20 N.A. 20
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 20 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 8 0 8 0 15 8 0 0 8 58 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 8 8 0 8 0 0 15 8 0 0 8 0 % E
% Phe: 8 0 0 8 8 8 0 0 0 0 0 0 8 8 0 % F
% Gly: 0 0 0 8 8 8 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 15 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 8 0 8 36 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 36 8 15 8 15 8 0 36 15 22 22 0 58 15 % K
% Leu: 8 0 0 0 8 0 8 8 0 15 0 15 8 0 0 % L
% Met: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 8 0 0 8 0 0 0 8 8 0 8 0 8 % N
% Pro: 8 0 0 36 0 8 0 8 0 36 43 50 0 15 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 8 22 8 8 43 0 0 0 8 8 58 % R
% Ser: 8 0 58 0 8 22 58 29 0 8 15 0 0 8 0 % S
% Thr: 29 15 0 0 0 0 0 22 0 8 0 0 0 0 8 % T
% Val: 0 29 0 8 0 0 8 8 0 0 0 0 0 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _