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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
2.73
Human Site:
T140
Identified Species:
4.62
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
T140
G
S
E
D
D
A
D
T
V
D
D
Y
G
A
D
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
M140
G
S
E
D
D
A
D
M
V
D
D
Y
G
A
D
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
M141
G
S
E
D
D
A
D
M
V
D
D
Y
G
A
D
Dog
Lupus familis
XP_854432
985
108067
S308
D
L
W
G
S
E
D
S
D
A
D
M
I
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
E141
S
N
S
E
D
E
E
E
K
L
L
P
I
E
R
Rat
Rattus norvegicus
XP_235295
772
84951
L141
S
E
D
E
E
E
K
L
L
P
I
E
R
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
V130
E
L
S
S
S
G
E
V
E
E
D
S
W
E
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
Y139
D
K
D
M
V
D
D
Y
G
A
D
E
G
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
D174
E
E
E
E
E
G
D
D
E
E
G
L
E
S
D
Honey Bee
Apis mellifera
XP_001121968
582
67009
K30
Q
G
D
P
T
F
P
K
G
V
L
V
K
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
D430
E
G
D
S
E
E
E
D
D
E
L
L
D
D
D
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
D119
P
L
A
E
D
F
L
D
G
S
D
N
E
E
V
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
E65
K
S
R
K
E
E
E
E
V
V
E
E
D
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
93.3
93.3
20
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
20
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
26.6
N.A.
26.6
33.3
N.A.
N.A.
20
N.A.
33.3
N.A.
46.6
13.3
N.A.
33.3
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
0
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
22
0
0
0
15
0
0
0
29
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
29
22
36
8
43
22
15
22
50
0
15
22
50
% D
% Glu:
22
15
29
29
29
36
29
15
15
22
8
22
15
29
15
% E
% Phe:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% F
% Gly:
22
15
0
8
0
15
0
0
22
0
8
0
29
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% I
% Lys:
8
8
0
8
0
0
8
8
8
0
0
0
8
8
0
% K
% Leu:
0
22
0
0
0
0
8
8
8
8
22
15
0
0
0
% L
% Met:
0
0
0
8
0
0
0
15
0
0
0
8
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
8
0
0
8
0
0
8
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
15
29
15
15
15
0
0
8
0
8
0
8
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
8
29
15
0
8
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
22
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _