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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP2
All Species:
15.15
Human Site:
T185
Identified Species:
25.64
UniProt:
P46087
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46087
NP_001028886.1
812
89302
T185
I
Q
W
S
E
E
E
T
E
D
E
E
E
E
K
Chimpanzee
Pan troglodytes
XP_001162276
812
89269
T185
I
Q
W
S
E
E
E
T
E
D
E
E
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001105884
811
89266
T186
V
Q
W
S
E
E
E
T
E
D
E
E
E
E
V
Dog
Lupus familis
XP_854432
985
108067
T357
G
Q
W
S
E
E
E
T
E
E
E
E
E
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q922K7
793
86733
D170
L
W
N
E
E
D
T
D
E
D
E
D
D
D
G
Rat
Rattus norvegicus
XP_235295
772
84951
G187
R
K
D
D
K
A
E
G
D
L
Q
I
N
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416502
682
76182
E159
D
Y
G
A
L
S
S
E
E
E
E
L
L
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922354
739
83513
D177
M
K
P
E
S
D
D
D
D
D
E
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610786
891
99823
D229
E
D
E
D
D
D
D
D
D
D
D
D
D
D
D
Honey Bee
Apis mellifera
XP_001121968
582
67009
K59
L
L
K
K
Q
N
I
K
E
K
L
K
E
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787141
1076
119756
S468
M
L
P
I
E
K
A
S
K
K
L
D
K
K
I
Poplar Tree
Populus trichocarpa
XP_002300386
476
53332
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194390
671
75524
I148
L
E
R
K
S
R
A
I
D
R
K
R
K
K
E
Baker's Yeast
Sacchar. cerevisiae
P40991
618
69794
D94
S
L
F
D
D
E
E
D
D
D
E
A
G
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.1
68.8
N.A.
75.8
75.1
N.A.
N.A.
55.5
N.A.
53
N.A.
41
37.5
N.A.
37.4
Protein Similarity:
100
99.3
96.1
73.8
N.A.
83.2
82
N.A.
N.A.
65.3
N.A.
66.5
N.A.
57.6
49.2
N.A.
49.7
P-Site Identity:
100
100
86.6
73.3
N.A.
26.6
6.6
N.A.
N.A.
13.3
N.A.
33.3
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
60
40
N.A.
N.A.
26.6
N.A.
73.3
N.A.
60
40
N.A.
53.3
Percent
Protein Identity:
37.9
N.A.
N.A.
39.7
37.4
N.A.
Protein Similarity:
47.6
N.A.
N.A.
55.6
52
N.A.
P-Site Identity:
0
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
0
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
15
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
22
15
22
15
29
36
50
8
22
15
15
8
% D
% Glu:
8
8
8
15
43
36
43
8
50
15
58
36
43
29
22
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
0
8
0
0
0
0
8
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
0
0
8
8
0
0
0
8
0
0
15
% I
% Lys:
0
15
8
15
8
8
0
8
8
15
8
8
15
22
15
% K
% Leu:
22
22
0
0
8
0
0
0
0
8
15
8
8
15
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
29
0
0
8
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
8
0
8
0
0
8
0
0
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
29
15
8
8
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
29
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
15
% V
% Trp:
0
8
29
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _