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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 16.06
Human Site: T505 Identified Species: 27.18
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 T505 A I D S V N A T S K T G G Y L
Chimpanzee Pan troglodytes XP_001162276 812 89269 T505 A I D S V N A T S K T G G Y L
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 T504 A I D S V N A T S K T G G Y L
Dog Lupus familis XP_854432 985 108067 T676 A I D S V N A T S K T G G Y L
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 A490 A I D S V N A A S K T G G Y L
Rat Rattus norvegicus XP_235295 772 84951 A485 A I D S V N A A S K T G G Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 G398 D M C C A P G G K T S Y I A Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 N434 I H R L G V T N A V I C N Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 K556 A I D C T D A K S S T G G Y I
Honey Bee Apis mellifera XP_001121968 582 67009 K298 T I R T N I L K T R R R D L A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 N782 A I D S I D A N S K T G G Y L
Poplar Tree Populus trichocarpa XP_002300386 476 53332 T192 A A A P G G K T T Y I A A L M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 L387 L K S L S A N L H R M G V T N
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 S334 Y I L Q A A S S F L P V I A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 0 N.A. 6.6 N.A. 60 6.6 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 13.3 N.A. 13.3 N.A. 73.3 26.6 N.A. 93.3
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 65 8 8 0 15 15 58 15 8 0 0 8 8 15 8 % A
% Cys: 0 0 8 15 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 58 0 0 15 0 0 0 0 0 0 8 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 15 8 8 8 0 0 0 65 58 0 0 % G
% His: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 72 0 0 8 8 0 0 0 0 15 0 15 0 8 % I
% Lys: 0 8 0 0 0 0 8 15 8 50 0 0 0 0 0 % K
% Leu: 8 0 8 15 0 0 8 8 0 8 0 0 0 15 58 % L
% Met: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 0 8 43 8 15 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 8 0 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 15 0 0 0 0 0 0 15 8 8 0 0 0 % R
% Ser: 0 0 8 50 8 0 8 8 58 8 8 0 0 0 0 % S
% Thr: 8 0 0 8 8 0 8 36 15 8 58 0 0 8 0 % T
% Val: 0 0 0 0 43 8 0 0 0 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 8 0 8 0 65 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _