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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 10
Human Site: T663 Identified Species: 16.92
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 T663 G A D S E L S T V P S V T K T
Chimpanzee Pan troglodytes XP_001162276 812 89269 T663 G A D S E L S T V P S V T K T
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 T662 G A D S E L S T V P S V R K T
Dog Lupus familis XP_854432 985 108067 S834 G I S K G T D S G L S T V S C
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 P648 G P G L S T E P S V P D A Q V
Rat Rattus norvegicus XP_235295 772 84951 P643 G P G L P T E P S V P N V Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 K556 K E G F T R F K D R R F H P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 A592 L S N T I P T A P K E T E N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 S714 K K K K R E E S K T K Y V A K
Honey Bee Apis mellifera XP_001121968 582 67009 K456 V S K D P S V K T N K D E I D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 G940 V D E G K G Q G G N G K G K K
Poplar Tree Populus trichocarpa XP_002300386 476 53332 R350 R P G F V R F R Q H R F H P S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 K545 G F F V A K L K K M S N A M Q
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 A492 D E A V I D Y A L R K R P N V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 93.3 13.3 N.A. 6.6 6.6 N.A. N.A. 0 N.A. 0 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 93.3 20 N.A. 13.3 13.3 N.A. N.A. 6.6 N.A. 26.6 N.A. 6.6 6.6 N.A. 20
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 8 0 8 0 0 15 0 0 0 0 15 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 8 8 22 8 0 8 8 0 8 0 0 15 0 0 8 % D
% Glu: 0 15 8 0 22 8 22 0 0 0 8 0 15 0 0 % E
% Phe: 0 8 8 15 0 0 15 0 0 0 0 15 0 0 0 % F
% Gly: 50 0 29 8 8 8 0 8 15 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 15 0 0 % H
% Ile: 0 8 0 0 15 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 15 8 15 15 8 8 0 22 15 8 22 8 0 29 15 % K
% Leu: 8 0 0 15 0 22 8 0 8 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 15 0 15 0 15 0 % N
% Pro: 0 22 0 0 15 8 0 15 8 22 15 0 8 15 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 0 0 0 0 15 15 % Q
% Arg: 8 0 0 0 8 15 0 8 0 15 15 8 8 0 0 % R
% Ser: 0 15 8 22 8 8 22 15 15 0 36 0 0 8 15 % S
% Thr: 0 0 0 8 8 22 8 22 8 8 0 15 15 0 22 % T
% Val: 15 0 0 15 8 0 8 0 22 15 0 22 22 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _