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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 12.12
Human Site: T695 Identified Species: 20.51
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 T695 G I R E P K V T G K L K Q R S
Chimpanzee Pan troglodytes XP_001162276 812 89269 T695 G I R E P K V T G K L K Q R S
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 T694 G I R E S K V T G K L K Q R S
Dog Lupus familis XP_854432 985 108067 V866 Q E I R G P K V T K K L K Q Q
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 Q680 K R S E K L K Q R G P K W K P
Rat Rattus norvegicus XP_235295 772 84951 P675 G K L K Q R G P K Q S A P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 F588 F I A K L K K F S N A I P K T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 K624 K P A S T P E K S S F E K K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 P746 K N E K S Q A P D K Q T N S S
Honey Bee Apis mellifera XP_001121968 582 67009 S488 C A N A R S E S G G I I V Y S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 V972 K S G S S S D V A E S K E E E
Poplar Tree Populus trichocarpa XP_002300386 476 53332 L382 F V A K L K K L S N S I P S A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 K577 S S D D D D E K A E A I E E L
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 S524 R G K K F H P S V K L A R R Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 6.6 N.A. N.A. 13.3 N.A. 0 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 93.3 20 N.A. 20 26.6 N.A. N.A. 33.3 N.A. 20 N.A. 26.6 26.6 N.A. 20
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 20 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 8 0 0 8 0 15 0 15 15 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 8 8 8 0 8 0 0 0 0 0 0 % D
% Glu: 0 8 8 29 0 0 22 0 0 15 0 8 15 15 8 % E
% Phe: 15 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 29 8 8 0 8 0 8 0 29 15 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 29 8 0 0 0 0 0 0 0 8 29 0 0 0 % I
% Lys: 29 8 8 36 8 36 29 15 8 43 8 36 15 22 0 % K
% Leu: 0 0 8 0 15 8 0 8 0 0 29 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 0 15 0 0 8 0 0 % N
% Pro: 0 8 0 0 15 15 8 15 0 0 8 0 22 8 15 % P
% Gln: 8 0 0 0 8 8 0 8 0 8 8 0 22 8 15 % Q
% Arg: 8 8 22 8 8 8 0 0 8 0 0 0 8 29 0 % R
% Ser: 8 15 8 15 22 15 0 15 22 8 22 0 0 15 36 % S
% Thr: 0 0 0 0 8 0 0 22 8 0 0 8 0 0 8 % T
% Val: 0 8 0 0 0 0 22 15 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _