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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR6
All Species:
24.85
Human Site:
S178
Identified Species:
60.74
UniProt:
P46095
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46095
NP_005275.1
362
37881
S178
Y
N
A
L
T
Y
Y
S
R
R
T
L
L
G
V
Chimpanzee
Pan troglodytes
Q9TUK4
317
34681
R160
H
S
I
V
T
L
P
R
A
R
R
A
I
A
A
Rhesus Macaque
Macaca mulatta
XP_001088851
362
37969
S178
Y
N
A
L
T
Y
Y
S
R
R
T
L
L
G
V
Dog
Lupus familis
XP_539080
470
49781
S286
Y
N
A
L
T
Y
Y
S
R
R
T
L
L
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6YNI2
363
38067
S179
Y
N
A
L
T
Y
Y
S
R
R
T
L
L
G
V
Rat
Rattus norvegicus
P51651
363
38097
S179
Y
N
A
L
T
Y
Y
S
R
R
T
L
L
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519402
379
40932
S195
Y
Y
A
L
T
Y
N
S
E
R
T
V
T
F
T
Chicken
Gallus gallus
XP_426182
675
72454
S491
Y
N
A
L
T
Y
Y
S
E
R
T
V
L
C
I
Frog
Xenopus laevis
NP_001104190
340
37459
L170
T
Y
T
M
L
I
L
L
W
A
L
C
I
C
I
Zebra Danio
Brachydanio rerio
Q9I8K8
370
41758
R167
Y
G
S
N
K
T
C
R
M
F
L
L
I
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
98.6
72.5
N.A.
93.9
93.9
N.A.
52.5
42
44.4
29.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.4
98.9
73.8
N.A.
96.1
96.1
N.A.
67
47.5
66.8
45.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
53.3
73.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
60
86.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
70
0
0
0
0
0
10
10
0
10
0
10
20
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
10
0
20
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
60
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
30
0
20
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
70
10
10
10
10
0
0
20
60
60
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
60
0
10
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
20
50
80
10
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
80
10
0
0
0
0
70
0
10
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
80
20
0
0
0
70
60
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _