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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR6 All Species: 17.88
Human Site: S58 Identified Species: 43.7
UniProt: P46095 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46095 NP_005275.1 362 37881 S58 N G S L E L S S Q L S A G P P
Chimpanzee Pan troglodytes Q9TUK4 317 34681 L48 P D G L F L S L G L V S L V E
Rhesus Macaque Macaca mulatta XP_001088851 362 37969 S58 N G S L E L S S Q L S A G P P
Dog Lupus familis XP_539080 470 49781 S166 N A S L E L S S Q L P A G P P
Cat Felis silvestris
Mouse Mus musculus Q6YNI2 363 38067 S59 N G S L E L S S Q L P A G P S
Rat Rattus norvegicus P51651 363 38097 S59 N G S L E L S S Q L P A G P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519402 379 40932 A70 S D L I G L N A S A A A S A Q
Chicken Gallus gallus XP_426182 675 72454 N355 M E P T A V L N E S S A A V P
Frog Xenopus laevis NP_001104190 340 37459 D54 D E S V N P W D I I L C V T G
Zebra Danio Brachydanio rerio Q9I8K8 370 41758 S54 I E S K Q S L S S L N I L F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.6 98.6 72.5 N.A. 93.9 93.9 N.A. 52.5 42 44.4 29.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.4 98.9 73.8 N.A. 96.1 96.1 N.A. 67 47.5 66.8 45.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 86.6 N.A. 86.6 86.6 N.A. 13.3 20 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 86.6 N.A. 86.6 86.6 N.A. 46.6 40 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 10 0 10 10 70 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 20 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 30 0 0 50 0 0 0 10 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 40 10 0 10 0 0 0 10 0 0 0 50 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 0 0 10 10 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 60 0 70 20 10 0 70 10 0 20 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 10 0 10 10 0 0 10 0 0 0 0 % N
% Pro: 10 0 10 0 0 10 0 0 0 0 30 0 0 50 40 % P
% Gln: 0 0 0 0 10 0 0 0 50 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 70 0 0 10 60 60 20 10 30 10 10 0 20 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 10 0 10 0 0 0 0 10 0 10 20 10 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _