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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR6 All Species: 27.27
Human Site: Y176 Identified Species: 66.67
UniProt: P46095 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46095 NP_005275.1 362 37881 Y176 S L Y N A L T Y Y S R R T L L
Chimpanzee Pan troglodytes Q9TUK4 317 34681 L158 R Y H S I V T L P R A R R A I
Rhesus Macaque Macaca mulatta XP_001088851 362 37969 Y176 S L Y N A L T Y Y S R R T L L
Dog Lupus familis XP_539080 470 49781 Y284 S L Y N A L T Y Y S R R T L L
Cat Felis silvestris
Mouse Mus musculus Q6YNI2 363 38067 Y177 S L Y N A L T Y Y S R R T L L
Rat Rattus norvegicus P51651 363 38097 Y177 S L Y N A L T Y Y S R R T L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519402 379 40932 Y193 S L Y Y A L T Y N S E R T V T
Chicken Gallus gallus XP_426182 675 72454 Y489 S L Y N A L T Y Y S E R T V L
Frog Xenopus laevis NP_001104190 340 37459 I168 T F T Y T M L I L L W A L C I
Zebra Danio Brachydanio rerio Q9I8K8 370 41758 T165 K V Y G S N K T C R M F L L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.6 98.6 72.5 N.A. 93.9 93.9 N.A. 52.5 42 44.4 29.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41.4 98.9 73.8 N.A. 96.1 96.1 N.A. 67 47.5 66.8 45.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 66.6 86.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 73.3 93.3 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 70 0 0 0 0 0 10 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 30 % I
% Lys: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 70 0 0 0 70 10 10 10 10 0 0 20 60 60 % L
% Met: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 60 0 10 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 20 50 80 10 0 0 % R
% Ser: 70 0 0 10 10 0 0 0 0 70 0 0 0 0 0 % S
% Thr: 10 0 10 0 10 0 80 10 0 0 0 0 70 0 10 % T
% Val: 0 10 0 0 0 10 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 10 80 20 0 0 0 70 60 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _