Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HTR3A All Species: 6.97
Human Site: T30 Identified Species: 17.04
UniProt: P46098 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46098 NP_000860 478 55280 T30 A R R S R N T T R P A L L R L
Chimpanzee Pan troglodytes Q5IS51 468 53049 I43 G L S E P S S I A K H E D S L
Rhesus Macaque Macaca mulatta Q866A2 502 56411 Q22 S L L H V S L Q G E F Q R K L
Dog Lupus familis XP_853967 442 50552 R24 A I D T P H S R N S A L Y R L
Cat Felis silvestris
Mouse Mus musculus P23979 487 56038 T34 R A T Q E D T T Q P A L L R L
Rat Rattus norvegicus P35563 483 55410 T35 A T Q A H S T T Q P A L L R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519474 387 44401
Chicken Gallus gallus Q9I8C7 452 50034 Q28 A P G C G A A Q G R L A H K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700338 466 53299 V23 R F A N A T L V R L N E F L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U298 474 55023 D23 I E R V Y S S D E E Y R L L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.9 27.8 42.2 N.A. 83.3 84 N.A. 62.5 31.7 N.A. 63.5 N.A. N.A. N.A. 29.2 N.A.
Protein Similarity: 100 50 48 59.4 N.A. 90.3 90.8 N.A. 70.9 50.6 N.A. 76.1 N.A. N.A. N.A. 51.8 N.A.
P-Site Identity: 100 6.6 6.6 33.3 N.A. 53.3 60 N.A. 0 13.3 N.A. 6.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 20 26.6 53.3 N.A. 66.6 86.6 N.A. 0 20 N.A. 13.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 10 10 10 10 10 10 0 10 0 40 10 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 0 10 0 0 0 0 10 0 0 % D
% Glu: 0 10 0 10 10 0 0 0 10 20 0 20 0 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % F
% Gly: 10 0 10 0 10 0 0 0 20 0 0 0 0 0 0 % G
% His: 0 0 0 10 10 10 0 0 0 0 10 0 10 0 0 % H
% Ile: 10 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 20 10 % K
% Leu: 0 20 10 0 0 0 20 0 0 10 10 40 40 20 70 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 10 0 10 0 0 0 0 % N
% Pro: 0 10 0 0 20 0 0 0 0 30 0 0 0 0 0 % P
% Gln: 0 0 10 10 0 0 0 20 20 0 0 10 0 0 0 % Q
% Arg: 20 10 20 0 10 0 0 10 20 10 0 10 10 40 0 % R
% Ser: 10 0 10 10 0 40 30 0 0 10 0 0 0 10 10 % S
% Thr: 0 10 10 10 0 10 30 30 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _