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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
23.03
Human Site:
S131
Identified Species:
42.22
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
S131
I
D
S
L
E
A
D
S
H
L
D
E
V
W
I
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
S131
I
D
S
L
E
A
D
S
H
L
D
E
V
W
I
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
I129
P
R
S
P
I
V
T
I
M
G
H
V
D
H
G
Dog
Lupus familis
XP_531830
727
81467
S131
I
D
S
L
E
A
H
S
H
L
D
E
V
W
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
S131
V
D
S
L
E
A
N
S
H
L
D
E
V
W
I
Rat
Rattus norvegicus
NP_001004254
727
81236
S131
I
D
S
L
E
A
N
S
H
L
D
E
V
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
P150
D
F
L
R
P
N
F
P
L
D
D
I
W
I
K
Chicken
Gallus gallus
XP_419288
726
81476
S131
V
D
S
L
E
P
D
S
I
L
Y
E
D
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
W129
R
S
G
M
K
Y
R
W
A
K
L
V
E
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
K123
I
I
Q
E
I
A
K
K
L
G
A
K
T
R
V
Honey Bee
Apis mellifera
NP_001011586
690
78106
K123
F
I
S
K
K
I
K
K
T
M
E
N
K
D
I
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
R125
A
A
F
S
F
K
P
R
F
V
N
G
P
P
K
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
S154
P
S
S
V
L
K
P
S
L
I
E
D
I
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
93.3
N.A.
6.6
60
N.A.
0
N.A.
13.3
13.3
0
13.3
P-Site Similarity:
100
100
6.6
93.3
N.A.
100
100
N.A.
6.6
66.6
N.A.
13.3
N.A.
26.6
33.3
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
47
0
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
47
0
0
0
0
24
0
0
8
47
8
16
8
0
% D
% Glu:
0
0
0
8
47
0
0
0
0
0
16
47
8
0
0
% E
% Phe:
8
8
8
0
8
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
16
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
39
0
8
0
0
8
0
% H
% Ile:
39
16
0
0
16
8
0
8
8
8
0
8
8
8
54
% I
% Lys:
0
0
0
8
16
16
16
16
0
8
0
8
8
0
24
% K
% Leu:
0
0
8
47
8
0
0
0
24
47
8
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
16
0
0
0
8
8
0
0
0
% N
% Pro:
16
0
0
8
8
8
16
8
0
0
0
0
8
8
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
8
0
0
8
8
0
0
0
0
0
8
0
% R
% Ser:
0
16
70
8
0
0
0
54
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
0
0
8
8
8
% T
% Val:
16
0
0
8
0
8
0
0
0
8
0
16
39
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
39
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _