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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
15.15
Human Site:
S23
Identified Species:
27.78
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
S23
T
I
Y
R
Q
L
H
S
L
C
Q
R
R
A
L
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
S23
T
I
Y
R
Q
L
H
S
L
C
Q
R
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
P21
V
T
K
K
E
E
R
P
Q
K
S
Q
L
S
S
Dog
Lupus familis
XP_531830
727
81467
S23
A
V
F
R
Q
L
H
S
L
G
Q
R
R
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
S23
T
I
C
R
Q
V
H
S
P
S
Q
R
R
L
L
Rat
Rattus norvegicus
NP_001004254
727
81236
S23
T
I
C
R
Q
L
H
S
L
S
Q
R
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
K42
W
W
F
S
L
C
P
K
R
G
F
G
E
Q
R
Chicken
Gallus gallus
XP_419288
726
81476
H23
H
G
A
C
R
Q
L
H
T
L
P
C
R
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
P21
S
C
W
H
H
G
G
P
P
L
S
P
V
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
H15
S
R
L
G
N
T
L
H
F
S
R
A
V
T
Q
Honey Bee
Apis mellifera
NP_001011586
690
78106
P15
Y
Q
H
Y
H
I
T
P
V
F
T
K
Q
K
K
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
Q17
L
R
T
A
T
S
R
Q
L
L
R
C
S
Q
V
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
D46
R
H
I
Q
V
L
A
D
L
G
L
S
K
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
0
66.6
N.A.
66.6
80
N.A.
0
6.6
N.A.
0
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
100
26.6
80
N.A.
73.3
80
N.A.
6.6
20
N.A.
20
N.A.
13.3
33.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
8
0
0
0
0
8
0
16
8
% A
% Cys:
0
8
16
8
0
8
0
0
0
16
0
16
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
16
0
0
0
0
0
8
8
8
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
8
0
0
24
0
8
0
0
0
% G
% His:
8
8
8
8
16
0
39
16
0
0
0
0
0
0
0
% H
% Ile:
0
31
8
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
0
0
8
0
8
0
8
8
8
8
% K
% Leu:
8
0
8
0
8
39
16
0
47
24
8
0
8
16
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
24
16
0
8
8
0
0
0
% P
% Gln:
0
8
0
8
39
8
0
8
8
0
39
8
8
16
8
% Q
% Arg:
8
16
0
39
8
0
16
0
8
0
16
39
47
8
8
% R
% Ser:
16
0
0
8
0
8
0
39
0
24
16
8
8
16
8
% S
% Thr:
31
8
8
0
8
8
8
0
8
0
8
0
0
8
0
% T
% Val:
8
8
0
0
8
8
0
0
8
0
0
0
16
0
16
% V
% Trp:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _