KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
19.09
Human Site:
S490
Identified Species:
35
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
S490
H
L
L
W
K
K
R
S
I
L
R
F
L
E
R
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
S490
H
L
L
W
K
K
R
S
I
L
R
F
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
S434
N
V
Q
W
K
K
R
S
L
L
Q
Y
L
E
I
Dog
Lupus familis
XP_531830
727
81467
S490
T
L
H
W
K
E
R
S
F
L
K
Y
Q
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
S490
S
L
H
W
K
E
R
S
Y
I
K
F
L
E
R
Rat
Rattus norvegicus
NP_001004254
727
81236
S490
S
L
H
W
K
Q
R
S
Y
I
K
Y
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
H508
V
K
N
W
R
E
R
H
F
M
Q
Y
Q
A
M
Chicken
Gallus gallus
XP_419288
726
81476
K490
H
L
T
W
R
Q
R
K
A
A
L
Y
K
A
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
R468
H
L
S
W
R
Q
R
R
A
A
L
Y
K
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
L465
A
E
R
E
A
R
R
L
A
G
R
F
R
M
R
Honey Bee
Apis mellifera
NP_001011586
690
78106
L448
K
M
L
K
I
K
R
L
F
G
K
D
R
K
I
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
L458
Y
L
S
N
R
Q
Q
L
L
D
R
G
Q
R
F
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
R507
K
M
H
W
R
E
I
R
A
E
K
V
K
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
53.3
46.6
N.A.
60
53.3
N.A.
13.3
26.6
N.A.
26.6
N.A.
26.6
20
13.3
13.3
P-Site Similarity:
100
100
86.6
73.3
N.A.
80
80
N.A.
46.6
46.6
N.A.
46.6
N.A.
33.3
40
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
31
16
0
0
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% D
% Glu:
0
8
0
8
0
31
0
0
0
8
0
0
0
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
24
0
0
31
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
8
0
0
0
% G
% His:
31
0
31
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
16
16
0
0
0
0
16
% I
% Lys:
16
8
0
8
47
31
0
8
0
0
39
0
24
8
8
% K
% Leu:
0
62
24
0
0
0
0
24
16
31
16
0
39
0
0
% L
% Met:
0
16
0
0
0
0
0
0
0
8
0
0
0
8
8
% M
% Asn:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
31
8
0
0
0
16
0
24
0
0
% Q
% Arg:
0
0
8
0
39
8
85
16
0
0
31
0
16
8
47
% R
% Ser:
16
0
16
0
0
0
0
47
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
16
0
0
47
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _