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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MTIF2 All Species: 27.88
Human Site: S513 Identified Species: 51.11
UniProt: P46199 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46199 NP_001005369.1 727 81317 S513 K E K R E R D S N V L S V I I
Chimpanzee Pan troglodytes XP_001155121 727 81419 S513 K E K R E R D S N V L S V I I
Rhesus Macaque Macaca mulatta XP_001114893 671 74635 S457 K E E M E R D S N V L P V I I
Dog Lupus familis XP_531830 727 81467 S513 K E K E E R D S P V L P I I I
Cat Felis silvestris
Mouse Mus musculus Q91YJ5 727 81328 S513 K E K V E R Q S N V L P I I I
Rat Rattus norvegicus NP_001004254 727 81236 S513 K E K V E R D S N V L P I I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510159 744 83619 S531 K E R I E S N S N K L T V V I
Chicken Gallus gallus XP_419288 726 81476 E513 K E R A E T D E N V L S I I I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001082793 705 78636 E491 S E R T E N E E L T M P I I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651621 696 76771 K486 Q V D E N E G K P R V S V I I
Honey Bee Apis mellifera NP_001011586 690 78106 T476 K N K N K N L T P A V N I I V
Nematode Worm Caenorhab. elegans NP_001023936 702 78116 S487 E K D V A D G S P K F R L I I
Sea Urchin Strong. purpuratus XP_001180329 739 82065 D526 K E S A P S G D P E L N L I I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 85.1 85.1 N.A. 81.2 83.3 N.A. 70 65.8 N.A. 57.6 N.A. 45.9 40.8 40.1 47.9
Protein Similarity: 100 99.8 89.4 92 N.A. 90.9 92.3 N.A. 82.3 80.6 N.A. 74.6 N.A. 63 60.5 59.4 65.7
P-Site Identity: 100 100 80 73.3 N.A. 73.3 80 N.A. 53.3 66.6 N.A. 26.6 N.A. 26.6 20 20 33.3
P-Site Similarity: 100 100 86.6 80 N.A. 80 86.6 N.A. 80 80 N.A. 53.3 N.A. 40 60 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 8 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 0 0 8 47 8 0 0 0 0 0 0 0 % D
% Glu: 8 77 8 16 70 8 8 16 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 47 93 93 % I
% Lys: 77 8 47 0 8 0 0 8 0 16 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 8 0 70 0 16 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 8 8 16 8 0 54 0 0 16 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 39 0 0 39 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 24 16 0 47 0 0 0 8 0 8 0 0 0 % R
% Ser: 8 0 8 0 0 16 0 62 0 0 0 31 0 0 0 % S
% Thr: 0 0 0 8 0 8 0 8 0 8 0 8 0 0 0 % T
% Val: 0 8 0 24 0 0 0 0 0 54 16 0 39 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _