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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
24.55
Human Site:
S612
Identified Species:
45
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
S612
D
L
Q
E
E
L
S
S
R
L
P
C
A
V
E
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
S612
D
L
Q
E
E
L
S
S
R
L
P
C
A
V
E
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
S556
D
L
Q
E
E
L
S
S
R
L
P
C
A
V
E
Dog
Lupus familis
XP_531830
727
81467
F612
D
V
Q
E
E
L
S
F
R
L
P
C
T
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
S612
D
L
Q
E
E
L
S
S
R
L
P
H
T
L
E
Rat
Rattus norvegicus
NP_001004254
727
81236
N612
D
L
Q
E
E
L
S
N
R
L
P
Y
K
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
S630
D
L
Q
E
E
L
S
S
R
L
A
P
S
V
E
Chicken
Gallus gallus
XP_419288
726
81476
S612
D
L
K
D
E
L
S
S
R
L
P
P
S
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
S590
E
L
K
E
D
L
S
S
K
L
P
P
T
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
P585
Q
L
S
S
K
L
P
P
V
E
V
E
E
V
L
Honey Bee
Apis mellifera
NP_001011586
690
78106
D575
N
I
K
K
E
I
Y
D
I
L
P
E
V
D
V
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
A585
S
L
K
G
E
L
S
A
R
I
P
K
L
T
E
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
N625
D
L
K
D
D
L
S
N
R
L
P
L
L
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
80
66.6
N.A.
53.3
N.A.
20
20
46.6
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
86.6
N.A.
80
N.A.
26.6
53.3
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
0
24
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
31
0
0
0
% C
% Asp:
70
0
0
16
16
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
62
77
0
0
0
0
8
0
16
8
8
70
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
39
8
8
0
0
0
8
0
0
8
8
0
0
% K
% Leu:
0
85
0
0
0
93
0
0
0
85
0
8
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
85
24
0
0
0
% P
% Gln:
8
0
54
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% R
% Ser:
8
0
8
8
0
0
85
54
0
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
24
16
0
% T
% Val:
0
8
0
0
0
0
0
0
8
0
8
0
8
62
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _