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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
42.73
Human Site:
T373
Identified Species:
78.33
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
T373
K
G
R
G
L
V
T
T
A
I
I
Q
R
G
T
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
T373
K
G
R
G
L
V
T
T
A
V
I
Q
R
G
T
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
A338
L
V
A
G
N
C
W
A
K
V
R
L
M
F
D
Dog
Lupus familis
XP_531830
727
81467
T373
K
G
R
G
P
V
T
T
A
I
I
Q
R
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
T373
K
G
R
G
P
V
T
T
A
I
I
Q
R
G
T
Rat
Rattus norvegicus
NP_001004254
727
81236
T373
K
G
R
G
P
V
T
T
A
I
I
Q
R
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
T391
K
G
K
G
P
V
T
T
A
I
I
Q
R
G
T
Chicken
Gallus gallus
XP_419288
726
81476
T373
K
G
K
G
P
V
T
T
A
I
I
Q
R
G
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
T351
K
G
K
G
P
V
T
T
A
I
I
Q
R
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
T355
P
R
R
G
K
L
S
T
A
I
V
S
R
G
T
Honey Bee
Apis mellifera
NP_001011586
690
78106
T338
I
G
R
G
K
L
V
T
A
L
I
Q
R
G
T
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
T349
H
G
I
G
K
V
C
T
L
V
V
S
R
G
T
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
T390
K
G
M
G
P
V
V
T
L
I
V
Q
R
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
93.3
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
N.A.
86.6
N.A.
53.3
66.6
46.6
60
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
73.3
80
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
77
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
85
0
100
0
0
0
0
0
0
0
0
0
93
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
70
70
0
0
0
8
% I
% Lys:
70
0
24
0
24
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
16
16
0
0
16
8
0
8
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% Q
% Arg:
0
8
54
0
0
0
0
0
0
0
8
0
93
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
0
62
93
0
0
0
0
0
0
85
% T
% Val:
0
8
0
0
0
77
16
0
0
24
24
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _