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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
40.61
Human Site:
T688
Identified Species:
74.44
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
T688
D
D
I
S
I
V
K
T
G
M
D
C
G
L
S
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
T688
D
D
I
S
I
V
K
T
G
M
D
C
G
L
S
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
T632
D
D
I
S
I
V
K
T
G
M
D
C
G
L
S
Dog
Lupus familis
XP_531830
727
81467
S688
D
D
I
S
V
I
K
S
G
M
D
C
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
T688
D
D
I
S
V
I
K
T
G
M
D
C
G
L
S
Rat
Rattus norvegicus
NP_001004254
727
81236
T688
D
D
V
L
V
I
K
T
G
V
D
C
G
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
T706
D
D
V
P
V
I
K
T
G
N
D
C
G
L
S
Chicken
Gallus gallus
XP_419288
726
81476
T688
D
D
V
Q
V
I
K
T
G
M
D
C
G
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
T666
D
D
V
L
T
V
K
T
G
M
E
C
G
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
K657
N
E
V
D
T
I
K
K
D
V
E
C
G
L
R
Honey Bee
Apis mellifera
NP_001011586
690
78106
T651
E
E
V
S
S
I
E
T
N
Y
E
C
G
L
R
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
T662
E
V
V
T
N
A
K
T
N
T
E
V
G
L
A
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
R701
D
D
V
S
S
V
K
R
G
L
E
C
G
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
100
80
N.A.
86.6
66.6
N.A.
66.6
73.3
N.A.
73.3
N.A.
26.6
33.3
26.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
86.6
N.A.
66.6
73.3
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% C
% Asp:
77
77
0
8
0
0
0
0
8
0
62
0
0
0
0
% D
% Glu:
16
16
0
0
0
0
8
0
0
0
39
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
77
0
0
0
100
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
39
0
24
54
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
93
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
16
0
0
0
0
0
8
0
0
0
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
16
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
24
% R
% Ser:
0
0
0
54
16
0
0
8
0
0
0
0
0
0
70
% S
% Thr:
0
0
0
8
16
0
0
77
0
8
0
0
0
0
0
% T
% Val:
0
8
62
0
39
39
0
0
0
16
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _