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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
7.58
Human Site:
Y112
Identified Species:
13.89
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
Y112
A
M
E
K
N
T
D
Y
V
Y
E
A
L
L
N
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
Y112
A
M
E
K
N
T
D
Y
V
Y
E
A
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
V110
V
K
K
N
K
D
A
V
R
R
P
Q
A
D
P
Dog
Lupus familis
XP_531830
727
81467
C112
A
M
E
K
D
I
D
C
V
F
E
A
L
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
C112
A
M
A
K
D
I
D
C
V
Y
E
A
L
L
N
Rat
Rattus norvegicus
NP_001004254
727
81236
C112
A
M
A
K
D
T
D
C
V
Y
E
A
L
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
H131
A
M
D
K
S
I
D
H
V
Y
E
S
L
W
N
Chicken
Gallus gallus
XP_419288
726
81476
H112
A
M
G
K
D
V
D
H
I
Y
E
A
L
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
M110
D
E
L
E
P
D
T
M
L
E
E
K
W
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
N104
L
Y
V
K
G
A
D
N
I
E
P
A
F
K
L
Honey Bee
Apis mellifera
NP_001011586
690
78106
I104
L
T
T
M
P
L
L
I
N
V
V
K
Y
L
G
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
S106
V
D
A
I
I
S
D
S
P
L
D
D
V
S
I
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
Y135
D
V
D
E
E
Y
I
Y
E
F
L
L
E
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
0
66.6
N.A.
73.3
80
N.A.
60
60
N.A.
6.6
N.A.
20
6.6
6.6
6.6
P-Site Similarity:
100
100
6.6
86.6
N.A.
80
86.6
N.A.
86.6
80
N.A.
26.6
N.A.
26.6
6.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
24
0
0
8
8
0
0
0
0
54
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% C
% Asp:
16
8
16
0
31
16
70
0
0
0
8
8
0
8
0
% D
% Glu:
0
8
24
16
8
0
0
0
8
16
62
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
16
0
0
8
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
24
8
8
16
0
0
0
0
8
8
% I
% Lys:
0
8
8
62
8
0
0
0
0
0
0
16
0
8
8
% K
% Leu:
16
0
8
0
0
8
8
0
8
8
8
8
54
47
8
% L
% Met:
0
54
0
8
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
16
0
0
8
8
0
0
0
0
0
47
% N
% Pro:
0
0
0
0
16
0
0
0
8
0
16
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
8
0
0
0
8
0
8
8
% S
% Thr:
0
8
8
0
0
24
8
0
0
0
0
0
0
8
0
% T
% Val:
16
8
8
0
0
8
0
8
47
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
8
0
0
0
8
0
24
0
47
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _