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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTIF2
All Species:
37.58
Human Site:
Y712
Identified Species:
68.89
UniProt:
P46199
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46199
NP_001005369.1
727
81317
Y712
V
G
D
R
I
V
C
Y
E
E
K
Q
I
Q
A
Chimpanzee
Pan troglodytes
XP_001155121
727
81419
Y712
V
G
D
R
I
V
C
Y
E
E
K
Q
I
Q
A
Rhesus Macaque
Macaca mulatta
XP_001114893
671
74635
Y656
V
G
D
R
I
V
C
Y
E
E
K
Q
I
Q
A
Dog
Lupus familis
XP_531830
727
81467
Y712
V
G
D
E
I
I
C
Y
E
E
K
E
V
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91YJ5
727
81328
Y712
P
G
D
Q
V
I
C
Y
E
E
N
K
V
P
T
Rat
Rattus norvegicus
NP_001004254
727
81236
Y712
V
G
D
Q
V
I
C
Y
E
E
N
K
V
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510159
744
83619
Y729
I
G
D
E
I
I
C
Y
E
E
K
E
V
L
Q
Chicken
Gallus gallus
XP_419288
726
81476
Y711
I
G
D
E
I
I
C
Y
E
E
K
E
I
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082793
705
78636
Y690
P
G
D
A
I
I
C
Y
S
E
S
E
V
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651621
696
76771
Y681
A
G
D
I
L
Q
C
Y
T
T
K
M
E
A
Q
Honey Bee
Apis mellifera
NP_001011586
690
78106
I675
P
G
D
T
I
I
C
I
N
I
K
R
Q
K
E
Nematode Worm
Caenorhab. elegans
NP_001023936
702
78116
Y686
E
D
D
Q
V
E
A
Y
E
K
R
T
I
T
Q
Sea Urchin
Strong. purpuratus
XP_001180329
739
82065
Y724
T
G
D
T
I
V
C
Y
E
I
E
R
I
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.1
85.1
N.A.
81.2
83.3
N.A.
70
65.8
N.A.
57.6
N.A.
45.9
40.8
40.1
47.9
Protein Similarity:
100
99.8
89.4
92
N.A.
90.9
92.3
N.A.
82.3
80.6
N.A.
74.6
N.A.
63
60.5
59.4
65.7
P-Site Identity:
100
100
100
60
N.A.
40
46.6
N.A.
53.3
66.6
N.A.
40
N.A.
33.3
33.3
26.6
53.3
P-Site Similarity:
100
100
100
80
N.A.
73.3
80
N.A.
80
86.6
N.A.
66.6
N.A.
40
53.3
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
8
0
0
0
0
0
0
8
24
% A
% Cys:
0
0
0
0
0
0
93
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
100
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
24
0
8
0
0
77
70
8
31
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
8
70
54
0
8
0
16
0
0
47
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
62
16
0
16
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% N
% Pro:
24
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% P
% Gln:
0
0
0
24
0
8
0
0
0
0
0
24
8
31
47
% Q
% Arg:
0
0
0
24
0
0
0
0
0
0
8
16
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% S
% Thr:
8
0
0
16
0
0
0
0
8
8
0
8
0
8
16
% T
% Val:
39
0
0
0
24
31
0
0
0
0
0
0
39
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _