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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NSF
All Species:
46.67
Human Site:
S538
Identified Species:
73.33
UniProt:
P46459
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46459
NP_006169.2
744
82594
S538
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Chimpanzee
Pan troglodytes
XP_511626
842
92301
S611
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Rhesus Macaque
Macaca mulatta
XP_001105450
854
93325
S648
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Dog
Lupus familis
XP_548044
752
83541
S538
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P46460
744
82595
S538
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Rat
Rattus norvegicus
Q9QUL6
744
82634
S538
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418094
740
82158
S538
S
D
R
T
P
L
V
S
V
L
L
E
G
P
P
Frog
Xenopus laevis
P23787
805
89193
K512
K
F
G
M
T
P
S
K
G
V
L
F
Y
G
P
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
K512
K
F
G
M
T
P
S
K
G
V
L
F
Y
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46461
745
82537
S538
P
E
S
S
G
L
V
S
V
L
V
A
G
A
P
Honey Bee
Apis mellifera
XP_001120201
743
82591
S541
T
E
G
S
G
L
V
S
V
L
L
E
G
P
P
Nematode Worm
Caenorhab. elegans
Q94392
824
91316
T615
P
E
N
S
G
F
R
T
V
V
L
A
G
A
A
Sea Urchin
Strong. purpuratus
NP_999752
746
82671
S542
S
D
R
V
P
L
A
S
M
L
M
G
G
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0Y8
742
81469
T532
S
T
R
S
P
L
V
T
C
L
L
E
G
P
S
Baker's Yeast
Sacchar. cerevisiae
P18759
758
84038
S559
S
D
K
S
R
L
V
S
L
L
I
H
G
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
86.8
98.1
N.A.
98.1
97.8
N.A.
N.A.
93.6
26.2
25
N.A.
62.4
65.8
50.6
64.8
Protein Similarity:
100
88.2
87.1
98.8
N.A.
99.7
99.7
N.A.
N.A.
96.5
44.2
44.4
N.A.
77.7
81.1
66.2
80.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
13.3
N.A.
46.6
66.6
20
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
20
20
N.A.
66.6
86.6
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
44.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
64.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
0
14
0
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
0
0
0
0
0
60
0
0
0
% E
% Phe:
0
14
0
0
0
7
0
0
0
0
0
14
0
0
0
% F
% Gly:
0
0
20
0
20
0
0
0
14
0
0
7
87
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
14
0
7
0
0
0
0
14
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
80
0
0
7
80
80
0
0
0
0
% L
% Met:
0
0
0
14
0
0
0
0
7
0
7
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
14
0
0
0
60
14
0
0
0
0
0
0
0
67
74
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
60
0
7
0
7
0
0
0
0
0
0
7
0
% R
% Ser:
67
0
7
34
0
0
14
74
0
0
0
0
0
0
14
% S
% Thr:
7
7
0
47
14
0
0
14
0
0
0
0
0
0
0
% T
% Val:
0
0
0
7
0
0
74
0
67
20
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _