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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRCC3 All Species: 4.55
Human Site: S193 Identified Species: 9.09
UniProt: P46736 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46736 NP_001018065.1 316 36072 S193 H G P R D F W S S S Q H I S I
Chimpanzee Pan troglodytes XP_521347 316 36067 S193 H G P R D F W S S S Q H I S I
Rhesus Macaque Macaca mulatta XP_001097957 291 33127 E183 I Q A Q K S S E Y E R I E I P
Dog Lupus familis XP_855467 270 30992 E167 E E R Y E R I E I P I H I V P
Cat Felis silvestris
Mouse Mus musculus P46737 291 33322 E183 I Q A Q K S S E Y E R I E I P
Rat Rattus norvegicus B2RYM5 291 32997 D183 V Q A Q K S S D Y E R I E I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514615 287 32741 I183 K S S E Y E R I E I P I H V V
Chicken Gallus gallus
Frog Xenopus laevis Q66GV6 261 29771 E158 S S E Y E R I E V P L H V V P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624978 164 18683 R61 H L D K K K D R V E I S T E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196828 282 31693 I179 P Q Y D R L E I A L H I I P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LT08 308 34335 L183 T T S N L G H L N K P S I Q A
Baker's Yeast Sacchar. cerevisiae P43588 306 34380 I189 K A N I Q A L I H G L N R H Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 91.7 81.3 N.A. 89.5 85.7 N.A. 78.4 N.A. 70.8 N.A. N.A. N.A. 32.5 N.A. 52.5
Protein Similarity: 100 100 91.7 81.9 N.A. 90.8 89.8 N.A. 84.8 N.A. 78.1 N.A. N.A. N.A. 40.8 N.A. 69.3
P-Site Identity: 100 100 0 13.3 N.A. 0 0 N.A. 0 N.A. 6.6 N.A. N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 13.3 20 N.A. 13.3 13.3 N.A. 6.6 N.A. 20 N.A. N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21.5 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. 38.9 38.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 0 0 9 0 0 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 17 0 9 9 0 0 0 0 0 0 0 % D
% Glu: 9 9 9 9 17 9 9 34 9 34 0 0 25 9 0 % E
% Phe: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 9 0 0 0 9 0 0 0 0 0 % G
% His: 25 0 0 0 0 0 9 0 9 0 9 34 9 9 0 % H
% Ile: 17 0 0 9 0 0 17 25 9 9 17 42 42 25 17 % I
% Lys: 17 0 0 9 34 9 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 9 0 0 9 9 9 9 0 9 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 9 0 17 0 0 0 0 0 0 17 17 0 0 9 42 % P
% Gln: 0 34 0 25 9 0 0 0 0 0 17 0 0 9 17 % Q
% Arg: 0 0 9 17 9 17 9 9 0 0 25 0 9 0 0 % R
% Ser: 9 17 17 0 0 25 25 17 17 17 0 17 0 17 0 % S
% Thr: 9 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 9 0 0 0 0 0 0 0 17 0 0 0 9 25 9 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 17 9 0 0 0 25 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _