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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRCC3
All Species:
6.36
Human Site:
S194
Identified Species:
12.73
UniProt:
P46736
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46736
NP_001018065.1
316
36072
S194
G
P
R
D
F
W
S
S
S
Q
H
I
S
I
E
Chimpanzee
Pan troglodytes
XP_521347
316
36067
S194
G
P
R
D
F
W
S
S
S
Q
H
I
S
I
E
Rhesus Macaque
Macaca mulatta
XP_001097957
291
33127
Y184
Q
A
Q
K
S
S
E
Y
E
R
I
E
I
P
I
Dog
Lupus familis
XP_855467
270
30992
I168
E
R
Y
E
R
I
E
I
P
I
H
I
V
P
H
Cat
Felis silvestris
Mouse
Mus musculus
P46737
291
33322
Y184
Q
A
Q
K
S
S
E
Y
E
R
I
E
I
P
I
Rat
Rattus norvegicus
B2RYM5
291
32997
Y184
Q
A
Q
K
S
S
D
Y
E
R
I
E
I
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514615
287
32741
E184
S
S
E
Y
E
R
I
E
I
P
I
H
V
V
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66GV6
261
29771
V159
S
E
Y
E
R
I
E
V
P
L
H
V
V
P
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624978
164
18683
V62
L
D
K
K
K
D
R
V
E
I
S
T
E
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196828
282
31693
A180
Q
Y
D
R
L
E
I
A
L
H
I
I
P
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT08
308
34335
N184
T
S
N
L
G
H
L
N
K
P
S
I
Q
A
L
Baker's Yeast
Sacchar. cerevisiae
P43588
306
34380
H190
A
N
I
Q
A
L
I
H
G
L
N
R
H
Y
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.7
81.3
N.A.
89.5
85.7
N.A.
78.4
N.A.
70.8
N.A.
N.A.
N.A.
32.5
N.A.
52.5
Protein Similarity:
100
100
91.7
81.9
N.A.
90.8
89.8
N.A.
84.8
N.A.
78.1
N.A.
N.A.
N.A.
40.8
N.A.
69.3
P-Site Identity:
100
100
0
13.3
N.A.
0
0
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
20
N.A.
13.3
13.3
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
0
9
0
0
9
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
17
0
9
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
9
17
9
9
34
9
34
0
0
25
9
0
17
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
9
0
9
34
9
9
0
17
% H
% Ile:
0
0
9
0
0
17
25
9
9
17
42
42
25
17
17
% I
% Lys:
0
0
9
34
9
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
9
9
9
0
9
17
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
0
17
0
0
0
0
0
0
17
17
0
0
9
42
9
% P
% Gln:
34
0
25
9
0
0
0
0
0
17
0
0
9
17
9
% Q
% Arg:
0
9
17
9
17
9
9
0
0
25
0
9
0
0
0
% R
% Ser:
17
17
0
0
25
25
17
17
17
0
17
0
17
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
17
0
0
0
9
25
9
9
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
17
9
0
0
0
25
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _