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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRCC3
All Species:
9.39
Human Site:
S258
Identified Species:
18.79
UniProt:
P46736
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46736
NP_001018065.1
316
36072
S258
H
S
L
T
H
L
D
S
V
T
K
I
H
N
G
Chimpanzee
Pan troglodytes
XP_521347
316
36067
S258
H
S
L
T
H
L
D
S
V
T
K
I
H
N
G
Rhesus Macaque
Macaca mulatta
XP_001097957
291
33127
L247
G
S
V
F
T
K
N
L
C
S
Q
M
S
A
V
Dog
Lupus familis
XP_855467
270
30992
S231
K
N
L
C
S
Q
M
S
A
V
S
G
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P46737
291
33322
L247
G
S
V
F
T
K
N
L
C
S
Q
M
S
A
V
Rat
Rattus norvegicus
B2RYM5
291
32997
L247
G
S
V
F
T
K
N
L
C
S
Q
M
S
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514615
287
32741
M247
T
K
N
L
C
S
Q
M
S
A
I
S
G
P
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66GV6
261
29771
S222
K
N
L
C
G
Q
M
S
A
I
S
G
P
L
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624978
164
18683
I125
D
H
G
F
V
G
L
I
F
S
V
F
S
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196828
282
31693
R243
S
V
C
H
Q
L
E
R
L
T
G
P
L
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LT08
308
34335
S249
Q
T
V
Q
E
M
L
S
L
A
A
K
Y
N
K
Baker's Yeast
Sacchar. cerevisiae
P43588
306
34380
T262
I
E
E
E
K
E
L
T
E
E
E
L
K
T
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
91.7
81.3
N.A.
89.5
85.7
N.A.
78.4
N.A.
70.8
N.A.
N.A.
N.A.
32.5
N.A.
52.5
Protein Similarity:
100
100
91.7
81.9
N.A.
90.8
89.8
N.A.
84.8
N.A.
78.1
N.A.
N.A.
N.A.
40.8
N.A.
69.3
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
40
20
N.A.
40
40
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
17
17
9
0
0
25
0
% A
% Cys:
0
0
9
17
9
0
0
0
25
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
9
9
9
9
9
0
9
9
9
0
0
9
0
% E
% Phe:
0
0
0
34
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
25
0
9
0
9
9
0
0
0
0
9
17
9
0
17
% G
% His:
17
9
0
9
17
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
9
0
0
0
0
0
0
9
0
9
9
17
0
0
0
% I
% Lys:
17
9
0
0
9
25
0
0
0
0
17
9
9
0
9
% K
% Leu:
0
0
34
9
0
25
25
25
17
0
0
9
9
25
25
% L
% Met:
0
0
0
0
0
9
17
9
0
0
0
25
0
0
0
% M
% Asn:
0
17
9
0
0
0
25
0
0
0
0
0
0
25
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
17
9
0
% P
% Gln:
9
0
0
9
9
17
9
0
0
0
25
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% R
% Ser:
9
42
0
0
9
9
0
42
9
34
17
9
34
0
9
% S
% Thr:
9
9
0
17
25
0
0
9
0
25
0
0
0
9
0
% T
% Val:
0
9
34
0
9
0
0
0
17
9
9
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _