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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPDA1
All Species:
27.27
Human Site:
T166
Identified Species:
50
UniProt:
P46926
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46926
NP_005462.1
289
32669
T166
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Chimpanzee
Pan troglodytes
XP_001139968
361
40677
T238
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Rhesus Macaque
Macaca mulatta
XP_001091343
361
40474
T238
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Dog
Lupus familis
XP_535222
289
32585
T166
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Cat
Felis silvestris
Mouse
Mus musculus
O88958
289
32532
T166
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Rat
Rattus norvegicus
NP_001128467
289
32561
T166
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006156
288
32245
T166
V
K
T
L
A
M
D
T
I
L
A
N
A
R
F
Frog
Xenopus laevis
Q6PA43
275
30901
I144
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
Zebra Danio
Brachydanio rerio
XP_684147
277
31333
G150
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMP9
273
30806
G142
I
G
G
I
G
P
D
G
H
I
A
F
N
E
P
Honey Bee
Apis mellifera
XP_393026
279
31676
G142
I
G
G
I
G
P
D
G
H
I
A
F
N
E
P
Nematode Worm
Caenorhab. elegans
Q9XVJ2
267
29895
P139
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
Sea Urchin
Strong. purpuratus
XP_790227
281
32124
I144
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
77.5
94.8
N.A.
95.8
95.8
N.A.
N.A.
90.6
83.7
81.3
N.A.
69.9
70.5
63.6
76.1
Protein Similarity:
100
80
77.8
98.2
N.A.
98.9
98.9
N.A.
N.A.
95.8
90.6
89.6
N.A.
80.9
80.2
75
86.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
0
6.6
N.A.
13.3
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
0
13.3
N.A.
33.3
33.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
54
0
0
0
16
0
70
0
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
70
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
16
0
16
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
16
0
16
0
8
54
% F
% Gly:
16
16
31
8
24
16
8
24
0
8
0
0
0
16
0
% G
% His:
8
0
0
0
0
0
16
0
16
0
8
0
0
0
0
% H
% Ile:
16
24
0
16
0
8
0
16
54
16
0
8
0
0
0
% I
% Lys:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
54
0
0
0
0
0
54
8
0
0
0
0
% L
% Met:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
16
54
16
0
8
% N
% Pro:
0
0
0
16
0
16
8
8
0
0
0
0
16
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
8
0
0
8
0
16
% S
% Thr:
0
0
54
0
0
0
0
54
0
0
0
0
0
0
8
% T
% Val:
54
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _