KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPDA1
All Species:
15.45
Human Site:
T277
Identified Species:
28.33
UniProt:
P46926
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46926
NP_005462.1
289
32669
T277
Y
S
I
K
E
K
E
T
E
K
S
Q
S
S
K
Chimpanzee
Pan troglodytes
XP_001139968
361
40677
T349
Y
S
I
K
E
K
E
T
E
K
S
Q
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001091343
361
40474
T349
Y
S
I
K
E
K
E
T
E
K
S
Q
S
S
K
Dog
Lupus familis
XP_535222
289
32585
T277
Y
S
I
K
E
K
E
T
E
K
N
Q
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
O88958
289
32532
I277
Y
S
I
K
E
K
E
I
Q
K
S
Q
S
A
K
Rat
Rattus norvegicus
NP_001128467
289
32561
I277
Y
S
I
K
E
K
E
I
Q
K
S
Q
S
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006156
288
32245
A277
Y
S
M
K
E
T
E
A
E
R
S
Q
S
K
K
Frog
Xenopus laevis
Q6PA43
275
30901
G257
K
T
V
K
Y
F
K
G
L
M
H
V
H
N
R
Zebra Danio
Brachydanio rerio
XP_684147
277
31333
V266
M
H
V
H
N
Q
L
V
E
P
T
L
S
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMP9
273
30806
G257
K
T
V
K
Y
F
K
G
I
L
R
D
L
D
E
Honey Bee
Apis mellifera
XP_393026
279
31676
I266
S
A
I
H
Q
K
L
I
E
E
D
G
N
T
I
Nematode Worm
Caenorhab. elegans
Q9XVJ2
267
29895
V251
L
E
L
K
V
K
T
V
K
Y
F
K
G
L
M
Sea Urchin
Strong. purpuratus
XP_790227
281
32124
S269
H
D
K
L
V
E
D
S
K
E
L
P
E
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
77.5
94.8
N.A.
95.8
95.8
N.A.
N.A.
90.6
83.7
81.3
N.A.
69.9
70.5
63.6
76.1
Protein Similarity:
100
80
77.8
98.2
N.A.
98.9
98.9
N.A.
N.A.
95.8
90.6
89.6
N.A.
80.9
80.2
75
86.1
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
66.6
6.6
20
N.A.
6.6
20
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
40
40
N.A.
33.3
53.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
8
8
0
8
0
% D
% Glu:
0
8
0
0
54
8
54
0
54
16
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
16
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
16
0
0
0
8
8
0
0
% G
% His:
8
8
0
16
0
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
54
0
0
0
0
24
8
0
0
0
0
0
8
% I
% Lys:
16
0
8
77
0
62
16
0
16
47
0
8
0
8
62
% K
% Leu:
8
0
8
8
0
0
16
0
8
8
8
8
8
8
0
% L
% Met:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
8
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
16
0
0
54
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% R
% Ser:
8
54
0
0
0
0
0
8
0
0
47
0
54
31
0
% S
% Thr:
0
16
0
0
0
8
8
31
0
0
8
0
0
8
0
% T
% Val:
0
0
24
0
16
0
0
16
0
0
0
8
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
0
16
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _