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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPDA1
All Species:
21.82
Human Site:
Y287
Identified Species:
40
UniProt:
P46926
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46926
NP_005462.1
289
32669
Y287
S
Q
S
S
K
K
P
Y
S
D
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001139968
361
40677
Y359
S
Q
S
S
K
K
P
Y
S
D
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001091343
361
40474
Y359
S
Q
S
S
K
K
P
Y
S
D
_
_
_
_
_
Dog
Lupus familis
XP_535222
289
32585
Y287
N
Q
P
S
E
K
P
Y
G
D
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O88958
289
32532
Y287
S
Q
S
A
K
K
P
Y
S
D
_
_
_
_
_
Rat
Rattus norvegicus
NP_001128467
289
32561
Y287
S
Q
S
A
K
K
P
Y
S
D
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006156
288
32245
Frog
Xenopus laevis
Q6PA43
275
30901
D267
H
V
H
N
R
L
V
D
P
L
L
S
M
K
K
Zebra Danio
Brachydanio rerio
XP_684147
277
31333
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMP9
273
30806
P267
R
D
L
D
E
G
S
P
L
E
G
Y
K
N
_
Honey Bee
Apis mellifera
XP_393026
279
31676
R276
D
G
N
T
I
L
R
R
S
V
Q
_
_
_
_
Nematode Worm
Caenorhab. elegans
Q9XVJ2
267
29895
H261
F
K
G
L
M
N
H
H
R
S
L
V
M
F
_
Sea Urchin
Strong. purpuratus
XP_790227
281
32124
K279
L
P
E
V
K
R
Q
K
K
K
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
77.5
94.8
N.A.
95.8
95.8
N.A.
N.A.
90.6
83.7
81.3
N.A.
69.9
70.5
63.6
76.1
Protein Similarity:
100
80
77.8
98.2
N.A.
98.9
98.9
N.A.
N.A.
95.8
90.6
89.6
N.A.
80.9
80.2
75
86.1
P-Site Identity:
100
100
100
60
N.A.
90
90
N.A.
N.A.
0
0
0
N.A.
0
9
0
10
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
0
13.3
0
N.A.
28.5
27.2
14.2
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
8
0
47
0
0
0
0
0
% D
% Glu:
0
0
8
0
16
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
8
0
0
8
0
0
8
0
8
0
0
0
0
% G
% His:
8
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
47
47
0
8
8
8
0
0
8
8
8
% K
% Leu:
8
0
8
8
0
16
0
0
8
8
16
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
8
0
8
8
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
0
47
8
8
0
0
0
0
0
0
% P
% Gln:
0
47
0
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
0
0
8
8
8
8
8
0
0
0
0
0
0
% R
% Ser:
39
0
39
31
0
0
8
0
47
8
0
8
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
8
0
0
8
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
54
62
62
62
77
% _