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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPDA1
All Species:
39.7
Human Site:
Y55
Identified Species:
72.78
UniProt:
P46926
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46926
NP_005462.1
289
32669
Y55
C
Y
K
K
L
I
E
Y
Y
K
N
G
D
L
S
Chimpanzee
Pan troglodytes
XP_001139968
361
40677
Y127
C
Y
K
K
L
I
E
Y
Y
K
N
G
D
L
S
Rhesus Macaque
Macaca mulatta
XP_001091343
361
40474
Y135
C
Y
K
K
L
I
E
Y
Y
K
N
G
D
L
S
Dog
Lupus familis
XP_535222
289
32585
Y55
C
Y
K
K
L
I
E
Y
C
K
N
G
D
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O88958
289
32532
Y55
C
Y
Q
K
L
I
E
Y
Y
K
N
G
D
L
S
Rat
Rattus norvegicus
NP_001128467
289
32561
Y55
C
Y
Q
K
L
I
E
Y
Y
K
N
G
D
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006156
288
32245
Y55
C
Y
R
K
L
V
E
Y
Y
K
N
G
D
L
S
Frog
Xenopus laevis
Q6PA43
275
30901
Y55
C
Y
K
K
L
I
E
Y
H
K
S
G
D
L
S
Zebra Danio
Brachydanio rerio
XP_684147
277
31333
Y55
C
Y
R
K
L
I
E
Y
H
K
S
G
D
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMP9
273
30806
F55
M
Y
K
E
L
I
E
F
H
K
Q
G
K
V
S
Honey Bee
Apis mellifera
XP_393026
279
31676
Y55
M
Y
R
K
L
I
E
Y
Y
K
A
G
K
I
S
Nematode Worm
Caenorhab. elegans
Q9XVJ2
267
29895
F54
M
Y
K
K
L
I
E
F
Y
N
A
G
V
I
S
Sea Urchin
Strong. purpuratus
XP_790227
281
32124
F55
M
Y
K
K
L
I
E
F
H
K
A
G
V
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80
77.5
94.8
N.A.
95.8
95.8
N.A.
N.A.
90.6
83.7
81.3
N.A.
69.9
70.5
63.6
76.1
Protein Similarity:
100
80
77.8
98.2
N.A.
98.9
98.9
N.A.
N.A.
95.8
90.6
89.6
N.A.
80.9
80.2
75
86.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
80
N.A.
53.3
66.6
60
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
80
80
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% A
% Cys:
70
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% D
% Glu:
0
0
0
8
0
0
100
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
31
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
93
0
0
0
0
0
0
0
16
0
% I
% Lys:
0
0
62
93
0
0
0
0
0
93
0
0
16
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
0
0
77
0
% L
% Met:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
54
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
100
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
100
0
0
0
0
0
77
62
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _