KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4
All Species:
4.55
Human Site:
S514
Identified Species:
8.33
UniProt:
P46934
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46934
NP_006145.2
1319
149059
S514
C
T
N
E
L
S
N
S
C
K
T
R
D
D
F
Chimpanzee
Pan troglodytes
XP_523083
895
103693
D197
P
G
W
E
E
R
Q
D
I
L
G
R
T
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001088005
1077
123165
D379
P
G
W
E
E
R
Q
D
I
L
G
R
T
Y
Y
Dog
Lupus familis
XP_851423
1251
141207
S514
F
T
N
E
L
S
N
S
L
K
H
S
C
K
P
Cat
Felis silvestris
Mouse
Mus musculus
P46935
887
102688
V189
P
Y
T
F
K
D
F
V
L
H
P
R
S
H
K
Rat
Rattus norvegicus
Q62940
887
102376
P189
F
K
D
F
V
L
H
P
R
S
H
K
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
V521
C
K
R
E
L
S
D
V
C
K
P
G
W
I
I
Chicken
Gallus gallus
XP_424462
1045
119140
I346
I
P
E
P
W
E
A
I
S
E
E
A
S
A
T
Frog
Xenopus laevis
Q2TAS2
751
86306
V53
Q
C
H
S
T
D
T
V
K
N
T
L
D
P
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L67
K
W
N
Q
H
Y
D
L
Y
I
G
K
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
S309
I
S
V
D
D
T
E
S
G
R
S
A
D
S
I
Honey Bee
Apis mellifera
XP_395191
782
90150
I84
P
V
W
E
E
E
F
I
F
R
V
K
P
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E111
T
S
S
G
R
P
R
E
E
T
I
T
R
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
67.5
86.5
N.A.
56.4
56
N.A.
70
40.6
27.6
28.2
N.A.
35.9
36.2
N.A.
N.A.
Protein Similarity:
100
67.2
72.4
89.8
N.A.
60.9
61.1
N.A.
80
53.7
40.1
39.7
N.A.
49.7
46.5
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
53.3
N.A.
6.6
0
N.A.
40
0
13.3
13.3
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
20
20
53.3
N.A.
6.6
26.6
N.A.
46.6
6.6
20
33.3
N.A.
46.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
16
0
8
0
% A
% Cys:
16
8
0
0
0
0
0
0
16
0
0
0
8
0
0
% C
% Asp:
0
0
8
8
8
16
16
16
0
0
0
0
24
24
8
% D
% Glu:
0
0
8
47
24
16
8
8
8
8
8
0
0
0
0
% E
% Phe:
16
0
0
16
0
0
16
0
8
0
0
0
0
0
8
% F
% Gly:
0
16
0
8
0
0
0
0
8
0
24
8
0
0
0
% G
% His:
0
0
8
0
8
0
8
0
0
8
16
0
0
8
0
% H
% Ile:
16
0
0
0
0
0
0
16
16
8
8
0
0
8
16
% I
% Lys:
8
16
0
0
8
0
0
0
8
24
0
24
0
8
16
% K
% Leu:
0
0
0
0
24
8
0
8
16
16
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
24
0
0
0
16
0
0
8
0
0
0
0
0
% N
% Pro:
31
8
0
8
0
8
0
8
0
0
16
0
8
8
8
% P
% Gln:
8
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
16
8
0
8
16
0
31
8
8
0
% R
% Ser:
0
16
8
8
0
24
0
24
8
8
8
8
31
8
8
% S
% Thr:
8
16
8
0
8
8
8
0
0
8
16
8
16
0
8
% T
% Val:
0
8
8
0
8
0
0
24
0
0
8
0
0
8
8
% V
% Trp:
0
8
24
0
8
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
8
0
0
8
0
0
0
0
16
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _