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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD4 All Species: 0
Human Site: T902 Identified Species: 0
UniProt: P46934 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46934 NP_006145.2 1319 149059 T902 P P G W E E R T H T D G R I F
Chimpanzee Pan troglodytes XP_523083 895 103693 E549 L R R A T V L E D S Y R R I M
Rhesus Macaque Macaca mulatta XP_001088005 1077 123165 E731 L R R A T V L E D S Y R R I M
Dog Lupus familis XP_851423 1251 141207 K885 E F F R R K L K K Q N D I P N
Cat Felis silvestris
Mouse Mus musculus P46935 887 102688 E541 L R R A N I L E D S Y R R I M
Rat Rattus norvegicus Q62940 887 102376 D541 R R A N I L E D S Y R R I M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511197 1255 141275 K889 E F F R K K M K K Q S D I P N
Chicken Gallus gallus XP_424462 1045 119140 F698 K L H R N N I F E E S Y R R I
Frog Xenopus laevis Q2TAS2 751 86306 I405 I E V S R E E I F E E S Y R Q
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 I419 I E V S R E E I F E E S Y R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 E661 I R R T S I L E D S Y R I I S
Honey Bee Apis mellifera XP_395191 782 90150 E436 V G R N N I L E D S Y R I I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 N463 H I K V R R K N I F E D A Y Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.1 67.5 86.5 N.A. 56.4 56 N.A. 70 40.6 27.6 28.2 N.A. 35.9 36.2 N.A. N.A.
Protein Similarity: 100 67.2 72.4 89.8 N.A. 60.9 61.1 N.A. 80 53.7 40.1 39.7 N.A. 49.7 46.5 N.A. N.A.
P-Site Identity: 100 13.3 13.3 0 N.A. 13.3 0 N.A. 0 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 20 20 13.3 N.A. 20 6.6 N.A. 13.3 6.6 13.3 13.3 N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 24 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 39 0 8 24 0 0 0 % D
% Glu: 16 16 0 0 8 24 24 39 8 24 24 0 0 0 0 % E
% Phe: 0 16 16 0 0 0 0 8 16 8 0 0 0 0 8 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 0 8 0 0 8 % G
% His: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 24 8 0 0 8 24 8 16 8 0 0 0 39 47 8 % I
% Lys: 8 0 8 0 8 16 8 16 16 0 0 0 0 0 0 % K
% Leu: 24 8 0 0 0 8 47 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 24 % M
% Asn: 0 0 0 16 24 8 0 8 0 0 8 0 0 0 16 % N
% Pro: 8 8 0 0 0 0 0 0 0 0 0 0 0 16 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 24 % Q
% Arg: 8 39 39 24 31 8 8 0 0 0 8 47 39 24 0 % R
% Ser: 0 0 0 16 8 0 0 0 8 39 16 16 0 0 16 % S
% Thr: 0 0 0 8 16 0 0 8 0 8 0 0 0 0 0 % T
% Val: 8 0 16 8 0 16 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 39 8 16 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _