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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEDD4 All Species: 0
Human Site: Y1024 Identified Species: 0
UniProt: P46934 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46934 NP_006145.2 1319 149059 Y1024 K E M F N P Y Y G L F E Y S A
Chimpanzee Pan troglodytes XP_523083 895 103693 D648 V Y H G K L L D G F F I R P F
Rhesus Macaque Macaca mulatta XP_001088005 1077 123165 D830 V Y H G K L L D G F F I R P F
Dog Lupus familis XP_851423 1251 141207 K987 E D H L S Y F K F I G R V A G
Cat Felis silvestris
Mouse Mus musculus P46935 887 102688 D640 V Y H G K L L D G F F I R P F
Rat Rattus norvegicus Q62940 887 102376 D640 V Y H G K L L D G F F I R P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511197 1255 141275 K991 E D H L S Y F K F I G R V A G
Chicken Gallus gallus XP_424462 1045 119140 L797 A V Y H G K L L D G F F I R P
Frog Xenopus laevis Q2TAS2 751 86306 D504 V F H G H Y I D G G F T L P F
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 D518 V F H G H Y I D G G F T L P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVI3 1007 114856 D760 V Y H G K L L D A F F I R P F
Honey Bee Apis mellifera XP_395191 782 90150 D535 V Y H G K L L D A F F I R P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 L562 G V F H R R F L D A F F V G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.1 67.5 86.5 N.A. 56.4 56 N.A. 70 40.6 27.6 28.2 N.A. 35.9 36.2 N.A. N.A.
Protein Similarity: 100 67.2 72.4 89.8 N.A. 60.9 61.1 N.A. 80 53.7 40.1 39.7 N.A. 49.7 46.5 N.A. N.A.
P-Site Identity: 100 13.3 13.3 0 N.A. 13.3 13.3 N.A. 0 6.6 13.3 13.3 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 13.3 13.3 40 N.A. 13.3 13.3 N.A. 40 6.6 20 20 N.A. 6.6 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 16 8 0 0 0 16 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 0 0 0 0 62 16 0 0 0 0 0 0 % D
% Glu: 16 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 16 8 8 0 0 24 0 16 47 85 16 0 0 62 % F
% Gly: 8 0 0 62 8 0 0 0 54 24 16 0 0 8 16 % G
% His: 0 0 77 16 16 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 0 16 0 47 8 0 0 % I
% Lys: 8 0 0 0 47 8 0 16 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 16 0 47 54 16 0 8 0 0 16 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 62 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 8 0 0 0 0 0 16 47 8 0 % R
% Ser: 0 0 0 0 16 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % T
% Val: 62 16 0 0 0 0 0 0 0 0 0 0 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 47 8 0 0 31 8 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _