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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4
All Species:
2.12
Human Site:
Y910
Identified Species:
3.89
UniProt:
P46934
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46934
NP_006145.2
1319
149059
Y910
H
T
D
G
R
I
F
Y
I
N
H
N
I
K
R
Chimpanzee
Pan troglodytes
XP_523083
895
103693
G557
D
S
Y
R
R
I
M
G
V
K
R
A
D
F
L
Rhesus Macaque
Macaca mulatta
XP_001088005
1077
123165
G739
D
S
Y
R
R
I
M
G
V
K
R
A
D
F
L
Dog
Lupus familis
XP_851423
1251
141207
K893
K
Q
N
D
I
P
N
K
F
E
M
K
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P46935
887
102688
G549
D
S
Y
R
R
I
M
G
V
K
R
A
D
L
L
Rat
Rattus norvegicus
Q62940
887
102376
V549
S
Y
R
R
I
M
G
V
K
R
A
D
F
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
R897
K
Q
S
D
I
P
N
R
F
E
M
K
L
R
R
Chicken
Gallus gallus
XP_424462
1045
119140
M706
E
E
S
Y
R
R
I
M
S
V
K
R
P
D
V
Frog
Xenopus laevis
Q2TAS2
751
86306
V413
F
E
E
S
Y
R
Q
V
M
K
M
R
P
K
D
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
V427
F
E
E
S
Y
R
Q
V
M
K
M
R
P
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
S669
D
S
Y
R
I
I
S
S
V
T
K
T
D
L
L
Honey Bee
Apis mellifera
XP_395191
782
90150
S444
D
S
Y
R
I
I
S
S
V
N
R
V
E
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E471
I
F
E
D
A
Y
Q
E
I
M
R
Q
T
P
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
67.5
86.5
N.A.
56.4
56
N.A.
70
40.6
27.6
28.2
N.A.
35.9
36.2
N.A.
N.A.
Protein Similarity:
100
67.2
72.4
89.8
N.A.
60.9
61.1
N.A.
80
53.7
40.1
39.7
N.A.
49.7
46.5
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
6.6
N.A.
13.3
0
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
26.6
N.A.
26.6
20
N.A.
20
6.6
20
20
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
24
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
8
24
0
0
0
0
0
0
0
8
31
8
16
% D
% Glu:
8
24
24
0
0
0
0
8
0
16
0
0
8
0
8
% E
% Phe:
16
8
0
0
0
0
8
0
16
0
0
0
8
16
0
% F
% Gly:
0
0
0
8
0
0
8
24
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
39
47
8
0
16
0
0
0
8
8
0
% I
% Lys:
16
0
0
0
0
0
0
8
8
39
16
16
0
24
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
16
24
39
% L
% Met:
0
0
0
0
0
8
24
8
16
8
31
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
16
0
0
16
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
0
0
0
24
8
0
% P
% Gln:
0
16
0
0
0
0
24
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
47
39
24
0
8
0
8
39
24
0
16
24
% R
% Ser:
8
39
16
16
0
0
16
16
8
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
0
24
39
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
39
8
16
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _