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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4
All Species:
0
Human Site:
Y941
Identified Species:
0
UniProt:
P46934
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46934
NP_006145.2
1319
149059
Y941
A
V
P
Y
S
R
D
Y
K
R
K
Y
E
F
F
Chimpanzee
Pan troglodytes
XP_523083
895
103693
F588
G
G
V
A
R
E
W
F
F
L
I
S
K
E
M
Rhesus Macaque
Macaca mulatta
XP_001088005
1077
123165
F770
G
G
V
A
R
E
W
F
F
L
I
S
K
E
M
Dog
Lupus familis
XP_851423
1251
141207
L924
A
D
F
L
K
A
R
L
W
I
E
F
D
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P46935
887
102688
F580
G
G
V
A
R
E
W
F
F
L
I
S
K
E
M
Rat
Rattus norvegicus
Q62940
887
102376
F580
G
V
A
R
E
W
F
F
L
I
S
K
E
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
L928
A
D
F
L
K
A
R
L
W
I
E
F
D
G
E
Chicken
Gallus gallus
XP_424462
1045
119140
W737
Y
G
G
V
A
R
E
W
F
F
L
L
S
K
E
Frog
Xenopus laevis
Q2TAS2
751
86306
W444
Y
G
G
V
A
R
E
W
L
Y
L
L
S
H
D
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
W458
Y
G
G
V
A
R
E
W
L
Y
L
L
S
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
F700
G
G
L
A
R
E
W
F
Y
L
L
S
K
E
M
Honey Bee
Apis mellifera
XP_395191
782
90150
F475
G
G
L
A
R
E
W
F
F
L
L
S
K
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E502
D
Y
G
G
V
S
R
E
F
F
F
L
L
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
67.5
86.5
N.A.
56.4
56
N.A.
70
40.6
27.6
28.2
N.A.
35.9
36.2
N.A.
N.A.
Protein Similarity:
100
67.2
72.4
89.8
N.A.
60.9
61.1
N.A.
80
53.7
40.1
39.7
N.A.
49.7
46.5
N.A.
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
0
20
N.A.
6.6
6.6
6.6
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
26.6
N.A.
13.3
26.6
N.A.
26.6
26.6
26.6
26.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
39
24
16
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
0
0
0
0
8
0
0
0
0
0
16
0
8
% D
% Glu:
0
0
0
0
8
39
24
8
0
0
16
0
16
39
31
% E
% Phe:
0
0
16
0
0
0
8
47
47
16
8
16
0
8
16
% F
% Gly:
47
62
31
8
0
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
24
24
0
0
0
0
% I
% Lys:
0
0
0
0
16
0
0
0
8
0
8
8
39
8
0
% K
% Leu:
0
0
16
16
0
0
0
16
24
39
39
31
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
39
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
39
31
24
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
0
0
0
8
39
24
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
16
24
24
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
39
24
16
0
0
0
0
0
0
% W
% Tyr:
24
8
0
8
0
0
0
8
8
16
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _