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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEDD4
All Species:
5.15
Human Site:
Y976
Identified Species:
9.44
UniProt:
P46934
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46934
NP_006145.2
1319
149059
Y976
A
T
V
L
E
D
S
Y
R
R
I
M
G
V
K
Chimpanzee
Pan troglodytes
XP_523083
895
103693
L613
S
A
T
D
N
Y
T
L
Q
I
N
P
N
S
G
Rhesus Macaque
Macaca mulatta
XP_001088005
1077
123165
L795
S
A
T
D
N
Y
T
L
Q
I
N
P
N
S
G
Dog
Lupus familis
XP_851423
1251
141207
F952
F
L
I
S
K
E
M
F
N
P
Y
Y
G
L
F
Cat
Felis silvestris
Mouse
Mus musculus
P46935
887
102688
L605
S
A
T
D
N
Y
T
L
Q
I
N
P
N
S
G
Rat
Rattus norvegicus
Q62940
887
102376
L605
A
T
E
D
N
Y
T
L
Q
I
N
P
N
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511197
1255
141275
F956
F
L
I
S
K
E
M
F
N
P
Y
Y
G
L
F
Chicken
Gallus gallus
XP_424462
1045
119140
T762
Y
S
A
T
D
N
Y
T
L
Q
I
N
P
N
S
Frog
Xenopus laevis
Q2TAS2
751
86306
T469
Y
S
R
D
D
I
Y
T
L
Q
I
N
P
D
S
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
T483
Y
S
R
D
D
I
Y
T
L
Q
I
N
P
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
L725
S
A
M
D
N
Y
T
L
Q
I
N
N
G
S
G
Honey Bee
Apis mellifera
XP_395191
782
90150
L500
S
A
T
D
N
Y
T
L
Q
I
N
P
F
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Y527
E
Y
S
A
Y
D
N
Y
T
I
Q
I
N
P
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.1
67.5
86.5
N.A.
56.4
56
N.A.
70
40.6
27.6
28.2
N.A.
35.9
36.2
N.A.
N.A.
Protein Similarity:
100
67.2
72.4
89.8
N.A.
60.9
61.1
N.A.
80
53.7
40.1
39.7
N.A.
49.7
46.5
N.A.
N.A.
P-Site Identity:
100
0
0
6.6
N.A.
0
13.3
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
20
20
40
N.A.
20
26.6
N.A.
40
33.3
26.6
26.6
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
39
8
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
24
16
0
0
0
0
0
0
0
16
0
% D
% Glu:
8
0
8
0
8
16
0
0
0
0
0
0
0
0
0
% E
% Phe:
16
0
0
0
0
0
0
16
0
0
0
0
8
0
16
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
47
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
16
0
0
0
54
31
8
0
0
0
% I
% Lys:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
16
0
8
0
0
0
47
24
0
0
0
0
16
0
% L
% Met:
0
0
8
0
0
0
16
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
47
8
8
0
16
0
47
31
39
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
16
0
39
24
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
47
24
8
0
0
0
0
% Q
% Arg:
0
0
16
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
39
24
8
16
0
0
8
0
0
0
0
0
0
47
24
% S
% Thr:
0
16
31
8
0
0
47
24
8
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
8
0
0
8
47
24
16
0
0
16
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _