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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YAP1
All Species:
18.48
Human Site:
S217
Identified Species:
36.97
UniProt:
P46937
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46937
NP_006097.1
504
54462
S217
M
N
V
T
A
P
T
S
P
P
V
Q
Q
N
M
Chimpanzee
Pan troglodytes
XP_001151402
488
52729
S217
M
N
V
T
A
P
T
S
P
P
V
Q
Q
N
M
Rhesus Macaque
Macaca mulatta
XP_001096954
125
14040
Dog
Lupus familis
XP_536601
465
50351
S238
M
N
Q
R
I
S
Q
S
A
P
V
K
Q
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P46938
488
52365
S202
L
N
V
P
A
P
A
S
P
A
V
P
Q
T
L
Rat
Rattus norvegicus
Q2EJA0
469
50483
S199
L
N
V
P
T
S
A
S
P
A
V
P
Q
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510207
422
46067
R196
T
T
S
W
L
D
P
R
L
D
P
R
F
A
M
Chicken
Gallus gallus
P46936
448
47804
S215
M
N
V
T
A
P
T
S
P
P
V
Q
Q
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001132952
442
48343
T197
D
G
W
E
Q
A
I
T
S
E
G
E
I
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q45VV3
418
46202
S196
N
N
P
N
A
N
P
S
S
Q
Q
Q
P
A
G
Honey Bee
Apis mellifera
XP_391844
511
54750
A237
N
V
A
A
V
A
A
A
V
D
N
G
K
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
R433
Q
N
V
P
Q
Y
K
R
D
F
R
R
K
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
21.4
77.9
N.A.
88.6
84.9
N.A.
75.5
78.9
N.A.
73.2
N.A.
20.4
28.5
N.A.
N.A.
Protein Similarity:
100
96.8
23.6
83.3
N.A.
92.6
88.8
N.A.
79.5
81.5
N.A.
78.9
N.A.
34.5
44.4
N.A.
N.A.
P-Site Identity:
100
100
0
40
N.A.
53.3
40
N.A.
6.6
93.3
N.A.
0
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
100
0
46.6
N.A.
66.6
53.3
N.A.
13.3
100
N.A.
13.3
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
42
17
25
9
9
17
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
17
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
0
9
0
9
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
9
17
0
0
% K
% Leu:
17
0
0
0
9
0
0
0
9
0
0
0
0
0
25
% L
% Met:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% M
% Asn:
17
67
0
9
0
9
0
0
0
0
9
0
0
25
0
% N
% Pro:
0
0
9
25
0
34
17
0
42
34
9
17
9
9
9
% P
% Gln:
9
0
9
0
17
0
9
0
0
9
9
34
50
0
0
% Q
% Arg:
0
0
0
9
0
0
0
17
0
0
9
17
0
0
0
% R
% Ser:
0
0
9
0
0
17
0
59
17
0
0
0
0
9
9
% S
% Thr:
9
9
0
25
9
0
25
9
0
0
0
0
0
17
0
% T
% Val:
0
9
50
0
9
0
0
0
9
0
50
0
0
9
0
% V
% Trp:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _