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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAAO
All Species:
24.85
Human Site:
Y118
Identified Species:
45.56
UniProt:
P46952
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46952
NP_036337.2
286
32542
Y118
T
E
L
D
G
L
R
Y
Y
V
G
D
T
M
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111024
286
32612
Y118
T
E
L
D
G
L
R
Y
Y
V
G
D
T
M
D
Dog
Lupus familis
XP_854526
421
45715
Y253
T
E
L
D
G
L
R
Y
Y
V
G
D
T
M
D
Cat
Felis silvestris
Mouse
Mus musculus
Q78JT3
286
32786
Y118
S
E
L
D
G
L
R
Y
Y
V
G
D
T
E
D
Rat
Rattus norvegicus
P46953
286
32564
Y118
T
E
L
D
G
L
R
Y
Y
V
G
D
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509925
169
19093
D8
Y
Y
V
G
E
S
T
D
V
L
Y
E
K
W
F
Chicken
Gallus gallus
XP_419453
287
33288
Y119
T
E
M
D
G
L
R
Y
Y
V
G
T
S
T
N
Frog
Xenopus laevis
Q6P7I0
282
32432
F118
T
E
K
D
G
L
R
F
Y
V
E
G
S
P
E
Zebra Danio
Brachydanio rerio
Q5U3F8
287
33220
Y121
K
E
T
D
G
L
R
Y
F
V
A
N
S
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19341
281
32209
F120
T
E
F
D
C
V
R
F
L
V
G
S
S
N
I
Sea Urchin
Strong. purpuratus
XP_784273
173
20285
D12
H
I
D
I
T
N
I
D
E
W
I
E
E
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47096
177
20216
N16
I
D
K
W
L
K
E
N
E
G
L
L
K
P
P
Red Bread Mold
Neurospora crassa
Q7SDX3
180
20539
L19
L
E
E
N
S
H
L
L
K
P
P
I
N
N
Y
Conservation
Percent
Protein Identity:
100
N.A.
97.1
56.5
N.A.
85.6
87.4
N.A.
32.5
59.2
59
54.7
N.A.
N.A.
N.A.
39.1
36.7
Protein Similarity:
100
N.A.
98.2
63.1
N.A.
92.6
94.4
N.A.
44.4
77
74.8
71.4
N.A.
N.A.
N.A.
61.5
48.6
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
0
66.6
53.3
46.6
N.A.
N.A.
N.A.
40
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
20
86.6
73.3
73.3
N.A.
N.A.
N.A.
60
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.5
42.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
70
0
0
0
16
0
0
0
39
0
0
39
% D
% Glu:
0
77
8
0
8
0
8
0
16
0
8
16
8
16
16
% E
% Phe:
0
0
8
0
0
0
0
16
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
62
0
0
0
0
8
54
8
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
8
0
0
0
8
8
0
0
8
% I
% Lys:
8
0
16
0
0
8
0
0
8
0
0
0
16
0
8
% K
% Leu:
8
0
39
0
8
62
8
8
8
8
8
8
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
24
0
% M
% Asn:
0
0
0
8
0
8
0
8
0
0
0
8
8
24
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
0
0
16
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
70
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
8
0
0
0
0
0
8
31
0
0
% S
% Thr:
54
0
8
0
8
0
8
0
0
0
0
8
39
16
0
% T
% Val:
0
0
8
0
0
8
0
0
8
70
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% W
% Tyr:
8
8
0
0
0
0
0
54
54
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _