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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STT3A All Species: 33.94
Human Site: S491 Identified Species: 67.88
UniProt: P46977 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46977 NP_689926.1 705 80530 S491 S S P S I V L S A R G G D G S
Chimpanzee Pan troglodytes XP_001143933 765 86861 S551 S S P S I V L S A R G G D G S
Rhesus Macaque Macaca mulatta XP_001108240 824 93330 S610 S S P S I V L S A R G G D G S
Dog Lupus familis XP_546418 705 80560 S491 S S P S I V L S A R G G D G S
Cat Felis silvestris
Mouse Mus musculus P46978 705 80579 S491 S S P S I V L S A R G G D G S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519530 681 77755 D479 D G S R I I F D D F R E A Y Y
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958866 705 80556 S491 S S P S I V L S A R G G D G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608425 713 80650 S502 S S P S I V L S A R S H D G G
Honey Bee Apis mellifera XP_392786 705 80434 S494 S S P S I V L S A R S P D G G
Nematode Worm Caenorhab. elegans P46975 757 85104 Q513 S H P S V V L Q S S T N N G D
Sea Urchin Strong. purpuratus XP_001175790 710 80959 S499 S S P S I V L S A R A G D G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39007 718 81510 P482 S S P S V V L P S Q T P D G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.1 85.5 99.5 N.A. 99.4 N.A. N.A. 91.7 N.A. N.A. 96.4 N.A. 76.5 78 53.7 81.9
Protein Similarity: 100 92.1 85.5 99.7 N.A. 99.7 N.A. N.A. 93.1 N.A. N.A. 98.5 N.A. 87 87.8 69.4 89.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 N.A. N.A. 100 N.A. 80 80 40 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 100 N.A. 80 80 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 53.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 68.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 75 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 9 0 0 0 84 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 50 59 0 92 25 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 84 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % N
% Pro: 0 0 92 0 0 0 0 9 0 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 0 75 9 0 0 0 0 % R
% Ser: 92 84 9 92 0 0 0 75 17 9 17 0 0 0 50 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % T
% Val: 0 0 0 0 17 92 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _