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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STT3A All Species: 35.45
Human Site: T606 Identified Species: 70.91
UniProt: P46977 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46977 NP_689926.1 705 80530 T606 M V R I G G S T D T G K H I K
Chimpanzee Pan troglodytes XP_001143933 765 86861 T666 M V R I G G S T D T G K H I K
Rhesus Macaque Macaca mulatta XP_001108240 824 93330 T725 M V R I G G S T D T G K H I K
Dog Lupus familis XP_546418 705 80560 T606 M V R I G G S T D T G K H I K
Cat Felis silvestris
Mouse Mus musculus P46978 705 80579 T606 M V R I G G S T E T G R H I K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519530 681 77755 Y594 H I K E H D Y Y T A T G E F R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_958866 705 80556 T606 M V R I G G S T D T G R H I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608425 713 80650 T617 M V R I G G S T D R G A H I R
Honey Bee Apis mellifera XP_392786 705 80434 T609 M V R I G G S T E K G K S I T
Nematode Worm Caenorhab. elegans P46975 757 85104 E628 M V R I A Q G E H P K D I R E
Sea Urchin Strong. purpuratus XP_001175790 710 80959 T614 M V R I G G S T E E G K H I K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39007 718 81510 I597 M I R I S E G I W P E E I K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.1 85.5 99.5 N.A. 99.4 N.A. N.A. 91.7 N.A. N.A. 96.4 N.A. 76.5 78 53.7 81.9
Protein Similarity: 100 92.1 85.5 99.7 N.A. 99.7 N.A. N.A. 93.1 N.A. N.A. 98.5 N.A. 87 87.8 69.4 89.8
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 0 N.A. N.A. 93.3 N.A. 80 73.3 26.6 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 20 N.A. N.A. 100 N.A. 86.6 80 33.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 53.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 68.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 50 0 0 9 0 0 0 % D
% Glu: 0 0 0 9 0 9 0 9 25 9 9 9 9 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 75 75 17 0 0 0 75 9 0 0 0 % G
% His: 9 0 0 0 9 0 0 0 9 0 0 0 67 0 0 % H
% Ile: 0 17 0 92 0 0 0 9 0 0 0 0 17 75 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 9 9 50 0 9 59 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 92 0 0 0 0 0 0 9 0 17 0 9 17 % R
% Ser: 0 0 0 0 9 0 75 0 0 0 0 0 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 75 9 50 9 0 0 0 9 % T
% Val: 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _